JMJD6 antibody (N-Term)

Catalog No. ABIN500088

Product Details anti-JMJD6 Antibody

Target: JMJD6 (Jumonji Domain Containing 6 (JMJD6))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JMJD6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody detects JMJD6.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Peptide affinity chromatography

Immunogen: JMJD6 antibody was raised against a 15 amino acid peptide from near the amino terminus of human JMJD6.

Isotype: IgG

Application Details

Application Notes: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Target Details for JMJD6

Target: JMJD6 (Jumonji Domain Containing 6 (JMJD6))

Alternative Name: JMJD6 / PTDSR (JMJD6 Products)

Synonyms: Ptdsr antibody, PSR antibody, PTDSR antibody, PTDSR1 antibody, psr antibody, ptdsr antibody, zfpsr antibody, zgc:66264 antibody, 5730436I23Rik antibody, D11Ertd195e antibody, PtdSerR antibody, mKIAA0585 antibody, GB15204 antibody, jmjd6 antibody, cg5383 antibody, ptdsr1 antibody, arginine demethylase and lysine hydroxylase antibody, jumonji domain containing 6 antibody, bifunctional arginine demethylase and lysyl-hydroxylase PSR antibody, jmjC domain-containing protein 4 homolog antibody, phosphatidylserine receptor antibody, jumonji domain containing 6 S homeolog antibody, jumonji domain containing 6 L homeolog antibody, Jmjd6 antibody, JMJD6 antibody, jmjd6 antibody, LOC411069 antibody, LOC5577546 antibody, CpipJ_CPIJ004848 antibody, CpipJ_CPIJ019866 antibody, jmjd6.S antibody, jmjd6.L antibody

Background: The jumonji domain-containing protein (JMJD) family is defined by the presence of the JmjC domain that is observed in several diverse species. JMJD6 was initially identified as a membrane protein that participates in phagocytosis but recent studies have shown that it has other functions when it is expressed in the cytosol and nucleus. JMJD6 is thought to play important roles in regulation of development and differentiation as knockdown experiments in mice resulted in neonatal lethality with severe defects in the morphology of numerous organs. JMJD6 also can catalyze the lysyl-hydroxylation of U2AF65, a protein involved with RNA splicing, suggesting that some of the functions attributed to JMJD6 may be due to its regulatory activity of RNA splicing.Synonyms: Histone arginine demethylase JMJD6, JmjC domain-containing protein 6, Jumonji domain-containing protein 6, KIAA0585, Phosphatidylserine receptor

Gene ID: 23210

UniProt: Q6NYC1