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NKIRAS1 antibody (C-Term)

NKIRAS1 Reactivity: Human, Mouse WB, IF, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN500112
  • Target See all NKIRAS1 Antibodies
    NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))
    Binding Specificity
    • 15
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 41
    • 30
    • 20
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 49
    • 7
    Rabbit
    Clonality
    • 49
    • 7
    Polyclonal
    Conjugate
    • 22
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This NKIRAS1 antibody is un-conjugated
    Application
    • 46
    • 27
    • 13
    • 13
    • 8
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Specificity
    This antibody is specific for kappaB-ras1 and has no cross-reactivity to kappaB-ras2.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, mouse
    Purification
    Peptide affinity chromatography
    Immunogen
    KappaB ras1 antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human KappaB ras1.
    Isotype
    IgG
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  • Application Notes
    ELISA. Western blot: 0.5 - 1 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))
    Alternative Name
    NKIRAS1 (NKIRAS1 Products)
    Synonyms
    NKIRAS1 antibody, KBRAS1 antibody, kappaB-Ras1 antibody, zgc:92823 antibody, kbras1 antibody, 2400004O09Rik antibody, NFKB inhibitor interacting Ras like 1 antibody, NFKB inhibitor interacting Ras-like 1 antibody, NFKB inhibitor interacting Ras-like 1 S homeolog antibody, NFKB inhibitor interacting Ras-like protein 1 antibody, NKIRAS1 antibody, nkiras1 antibody, nkiras1.S antibody, Nkiras1 antibody
    Background
    KappaB ras-1 (kappaB-ras-1) and kappaB-ras-2 are two small proteins that similar to Ras-like small GTPases that associate with IkappaB (IkappaB), an inhibitor of the transcription factor NF-kappaB. IkappaB exists in two homologous forms, IkappaB-alpha and IkappaB-beta, although IkappaB-beta contains a unique 47-amino acid region within its ankyrin domain. While inactive IkappaB-alpha-NF-kappaB complexes can shuttle in and out of the nucleus, IkappaB-beta-NF-kappaB complexes are retained exclusively in the cytoplasm. It is suggested that kappaB-ras proteins preferentially bind to the IkappaB-beta form through this unique insert within the ankyrin region, thus modulating the cellular location of IkappaB-beta and regulating the rate of degradation of IkappaB-beta.Synonyms: KBRAS1, NF-kappa-B inhibitor-interacting Ras-like protein 1
    Gene ID
    28512
    UniProt
    Q9NYS0
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