Klra3 antibody (C-Term)

Catalog No. ABIN500132

Product Details anti-Klra3 Antibody

Target: Klra3 (Killer Cell Lectin-Like Receptor, Subfamily A, Member 3 (Klra3))

Binding Specificity: C-Term

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Klra3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects KLRA3. It may cross-react with other LY49 receptors.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse.

Purification: Peptide affinity chromatography

Immunogen: KLRA3 antibody was raised against a 14 amino acid peptide near the carboxy terminus of mouse KLRA3.

Isotype: IgG

Application Details

Application Notes: ELISA. Western blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Target Details for Klra3

Target: Klra3 (Killer Cell Lectin-Like Receptor, Subfamily A, Member 3 (Klra3))

Alternative Name: KLRA3 (Klra3 Products)

Background: KLRA3 (also known as Ly49C) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA3 is thought to be an inhibitory receptor, recognizing peptide -receptive H-2Kb.Synonyms: 5E6, Killer cell lectin-like receptor 3, Ly-49c, Ly49C, Lymphocyte antigen 49c, T-cell surface glycoprotein Ly-49C

Gene ID: 16640

NCBI Accession: NP_034781

UniProt: Q64329