METTL7A antibody (Center)

Catalog No. ABIN500274

Product Details anti-METTL7A Antibody

Target: METTL7A (Methyltransferase Like 7A (METTL7A))

Binding Specificity: Center

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This METTL7A antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Specificity: This antibody detects METTL7A at center. It is predicted to not cross-react with MettL7B.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse

Purification: Peptide affiniity chromatography

Immunogen: MettL7A antibody was raised against a 13 amino acid peptide near the center of human MettL7A.

Isotype: IgG

Application Details

Application Notes: ELISA. Western blot: 2 - 4 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Target Details for METTL7A

Target: METTL7A (Methyltransferase Like 7A (METTL7A))

Alternative Name: METTL7A (METTL7A Products)

Synonyms: AAM-B antibody, 2210414H16Rik antibody, 3300001H21Rik antibody, Aam-B antibody, Mettl7a antibody, UbiE1 antibody, RGD1308407 antibody, MGC82719 antibody, zgc:153889 antibody, MGC145311 antibody, DKFZp459L026 antibody, methyltransferase like 7A antibody, methyltransferase like 7A1 antibody, methyltransferase like 7A L homeolog antibody, METTL7A antibody, Mettl7a1 antibody, Mettl7a antibody, mettl7a.L antibody, mettl7a antibody

Background: MettL7A belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis. At least two isoforms of MettL7A are known to exisit.Synonyms: Methyltransferase-like protein 7A, PRO0066, UNQ1902/PRO4348

Gene ID: 25840

NCBI Accession: NP_054752

UniProt: Q9H8H3