ProSAPiP1 antibody (C-Term)

Catalog No. ABIN500541

Product Details anti-ProSAPiP1 Antibody

Target: ProSAPiP1 (PROSAPIP1) (ProSAP-Interacting Protein 1 (PROSAPIP1))

Binding Specificity: C-Term

Reactivity: Mouse, Rat, Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ProSAPiP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody detects Prosapip1. It will not cross-react with Prosapip2.

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse, Rat.

Purification: Peptide Affinity Chromatography

Immunogen: A 16 amino acid peptide from near the carboxy terminus of Human Prosapip1.

Isotype: IgG

Application Details

Application Notes: ELISA. Western blot: 1-2 μg/mL. Immunohistochemistry on Paraffin Sections. Recommended Positive Control. SK-N-SH Cell Lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for ProSAPiP1

Target: ProSAPiP1 (PROSAPIP1) (ProSAP-Interacting Protein 1 (PROSAPIP1))

Alternative Name: PROSAPIP1 (PROSAPIP1 Products)

Synonyms: PROSAPIP1 antibody, RP5-1187M17.10 antibody, Prosapip1 antibody, leucine zipper tumor suppressor family member 3 antibody, leucine zipper, putative tumor suppressor family member 3 antibody, LZTS3 antibody, Lzts3 antibody

Background: Prosapip1 is a binding partner of the postsynaptic density (PSD) protein ProSAP2/Shank3, a major scaffolding protein in excitatory brain synapses. Prosapip1 is thought to bind ProSAP2/Shank3 through ProSAP2/Shank3's PDZ domain and link it in turn to the Spine-associated Rap-Gap (SPAR). Prosapip1 shares significant homology with another PSD protein, PSD-Zip70, with both coding for a Fez1 domain that can be found in a total of four related protein, forming a novel family of scaffolding molecules termed 'Fezzins'. Recent studies show that Prosapip1 can be found in endocrine cells in which it is localized primarily in the hormone-storing compartment of these cells, suggesting that Prosapip1 may have other functions in non-neuronal cells.Synonyms: KIAA0552, ProSAP-interacting protein 1

Gene ID: 9762

NCBI Accession: NP_055546

UniProt: O60299