RGPD5 / RGPD6 (Center) antibody
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- Target
- RGPD5 / RGPD6
- Binding Specificity
- Center
- Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- Un-conjugated
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Application
- Enzyme Immunoassay (EIA), Western Blotting (WB)
- Specificity
- This antibody detects RGPD5.
- Cross-Reactivity (Details)
- Species reactivity (tested):Human
- Purification
- Peptide affinity chromatography
- Immunogen
- RGPD5 antibody was raised against a 23 amino acid peptide from near the center of human RGPD5.
- Isotype
- IgG
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- Application Notes
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ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Buffer
- PBS containing 0.02 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- Target
- RGPD5 / RGPD6
- Synonyms
- BS-63 antibody, BS63 antibody, RGP5 antibody, RANBP2-like and GRIP domain containing 5 antibody, RGPD5 antibody
- Background
- The RANBP2-like and GRIP domain containing 5 protein (RGPD5) has high similarity to RANBP2, a large RAN-binding protein localized at the cytoplasmic side of the nuclear pore complex. The gene coding for RGPD5 is thought to have arisen from a gene duplication event of RANBP2 as these highly homologous genes are located close to each other at chromosome 2q11-q12. RGPD5 was identified as an HIV dependency factor (HDF), suggesting that RGPD5 may be an important drug target in HIV treatment. At least two isoforms of RGPD5 are known to exist, of which the shorter isoform is expressed primarily in testis, while the longer of the two is expressed at low levels in a number of somatic tissues.Synonyms: BS-63, RANBP2-like and GRIP domain-containing protein 5/6, RGP5, RGP6, RGP7, RGPD7, Ran-binding protein 2-like 1/2, RanBP2-like 1/2, RanBP2L1, RanBP2L2
- Gene ID
- 84220
- NCBI Accession
- NP_005045
- UniProt
- Q99666
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