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RGPD5 / RGPD6 (Center) antibody

Reactivity: Human EIA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN500585
  • Target
    RGPD5 / RGPD6
    Binding Specificity
    Center
    Reactivity
    Human
    Host
    • 1
    Rabbit
    Clonality
    • 1
    Polyclonal
    Conjugate
    • 1
    Un-conjugated
    Application
    • 1
    • 1
    • 1
    Enzyme Immunoassay (EIA), Western Blotting (WB)
    Specificity
    This antibody detects RGPD5.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human
    Purification
    Peptide affinity chromatography
    Immunogen
    RGPD5 antibody was raised against a 23 amino acid peptide from near the center of human RGPD5.
    Isotype
    IgG
  • Application Notes
    ELISA. Western blot: 1 - 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    RGPD5 / RGPD6
    Synonyms
    BS-63 antibody, BS63 antibody, RGP5 antibody, RANBP2-like and GRIP domain containing 5 antibody, RGPD5 antibody
    Background
    The RANBP2-like and GRIP domain containing 5 protein (RGPD5) has high similarity to RANBP2, a large RAN-binding protein localized at the cytoplasmic side of the nuclear pore complex. The gene coding for RGPD5 is thought to have arisen from a gene duplication event of RANBP2 as these highly homologous genes are located close to each other at chromosome 2q11-q12. RGPD5 was identified as an HIV dependency factor (HDF), suggesting that RGPD5 may be an important drug target in HIV treatment. At least two isoforms of RGPD5 are known to exist, of which the shorter isoform is expressed primarily in testis, while the longer of the two is expressed at low levels in a number of somatic tissues.Synonyms: BS-63, RANBP2-like and GRIP domain-containing protein 5/6, RGP5, RGP6, RGP7, RGPD7, Ran-binding protein 2-like 1/2, RanBP2-like 1/2, RanBP2L1, RanBP2L2
    Gene ID
    84220
    NCBI Accession
    NP_005045
    UniProt
    Q99666
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