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Scavenger Receptor Class B, Member 1 (SCARB1) (N-Term) antibody

Details for Product No. ABIN500682
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Antigen
Synonyms cb1015, SCARB1, Scarb1, CD36L1, CLA-1, CLA1, HDLQTL6, SR-BI, SRB1, AI120173, CD36, Cd36l1, Cla-1, Cla1, D5Ertd460e, Hdlq1, Hlb398, SR-B1, SRBI, Srb1, mSR-BI
Epitope
N-Term
(16), (12), (7), (5), (3)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(47), (47), (40), (17), (17), (17), (4), (2)
Host
Rabbit
(59), (8), (4)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(50), (20), (20), (18), (14), (13), (11), (10), (7), (6), (3), (1)
Pubmed 2 references available
Quantity 0.1 mg
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Catalog No. ABIN500682
401.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen SCARB1 antibody was raised against a 15 amino acid peptide near the amino terminus of human SCARB1.
Isotype IgG
Specificity This antibody detects SCARB1. Species Reactivity: Tested: Human, mouse, rat
Purification Peptide affinity chromatography
Alternative Name SCARB1
Background Scavenger receptor class B member 1 (SCARB1), also known as SR-BI, is part of the scavenger receptor superfamily, which is composed of many members with diverse structures, expression patterns, and functions. SCARB1 is a multi-ligand cell-surface receptor that mediates the selective uptake of lipid from HDL cholesterol into cells and is expressed in steroidogenic tissues in adult animals. Other ligands of SCARB1 include native, acetylated, or oxidized LDL and anionic phospholipids. SCARB1-deficient mice have elevated HDL levels and increased susceptibility to atherosclerosis on fat feeding, indicating its importance in the regulation of cholesterol homeostasis. Along with CLDN1, LDL-R, and the tetraspanin superfamily member CD81, SCARB1 has been reported to be an entry factor for the Hepatitis C virus. At least two isoforms of SCARB1 are known to exist.
Alternate names: CD36 and LIMPII analogous 1, CD36 antigen-like 1, CD36L1, CLA-1, CLA1, Collagen type I receptor thrombospondin receptor-like 1, SR-BI, SRB1, Scavenger receptor class B member 1
Gene ID 949
NCBI Accession 37999904
UniProt Q8WTV0
Application Notes ELISA. Western blot: 1 - 2 μg/ml. Immunohistochemistry on paraffin sections. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Buffer PBS containing 0.02% sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Expiry Date 12 months
Background publications Acton, Rigotti, Landschulz et al.: "Identification of scavenger receptor SR-BI as a high density lipoprotein receptor." in: Science (New York, N.Y.), Vol. 271, Issue 5248, pp. 518-20, 1996 (PubMed).

Greaves, Gough, Gordon: "Recent progress in defining the role of scavenger receptors in lipid transport, atherosclerosis and host defence." in: Current opinion in lipidology, Vol. 9, Issue 5, pp. 425-32, 1999 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN500682
401.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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