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SCARB1 antibody (N-Term)

SCARB1 Reactivity: Human, Rat, Mouse WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN500682
  • Target See all SCARB1 Antibodies
    SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))
    Binding Specificity
    • 11
    • 9
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 51
    • 29
    • 28
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 51
    • 8
    • 2
    Rabbit
    Clonality
    • 41
    • 20
    Polyclonal
    Conjugate
    • 35
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This SCARB1 antibody is un-conjugated
    Application
    • 38
    • 19
    • 15
    • 10
    • 10
    • 8
    • 8
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects SCARB1.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Peptide affinity chromatography
    Immunogen
    SCARB1 antibody was raised against a 15 amino acid peptide near the amino terminus of human SCARB1.
    Isotype
    IgG
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  • Application Notes
    ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))
    Alternative Name
    SCARB1 (SCARB1 Products)
    Synonyms
    cb1015 antibody, SCARB1 antibody, Scarb1 antibody, CD36L1 antibody, CLA-1 antibody, CLA1 antibody, HDLQTL6 antibody, SR-BI antibody, SRB1 antibody, AI120173 antibody, CD36 antibody, Cd36l1 antibody, Cla-1 antibody, Cla1 antibody, D5Ertd460e antibody, Hdlq1 antibody, Hlb398 antibody, SR-B1 antibody, SRBI antibody, Srb1 antibody, mSR-BI antibody, scavenger receptor class B, member 1 antibody, scavenger receptor class B member 1 antibody, scarb1 antibody, SCARB1 antibody, Scarb1 antibody, CpipJ_CPIJ014332 antibody, CpipJ_CPIJ019101 antibody
    Background
    Scavenger receptor class B member 1 (SCARB1), also known as SR-BI, is part of the scavenger receptor superfamily, which is composed of many members with diverse structures, expression patterns, and functions. SCARB1 is a multi-ligand cell-surface receptor that mediates the selective uptake of lipid from HDL cholesterol into cells and is expressed in steroidogenic tissues in adult animals. Other ligands of SCARB1 include native, acetylated, or oxidized LDL and anionic phospholipids. SCARB1-deficient mice have elevated HDL levels and increased susceptibility to atherosclerosis on fat feeding, indicating its importance in the regulation of cholesterol homeostasis. Along with CLDN1, LDL-R, and the tetraspanin superfamily member CD81, SCARB1 has been reported to be an entry factor for the Hepatitis C virus. At least two isoforms of SCARB1 are known to exist.Synonyms: CD36 and LIMPII analogous 1, CD36 antigen-like 1, CD36L1, CLA-1, CLA1, Collagen type I receptor thrombospondin receptor-like 1, SR-BI, SRB1, Scavenger receptor class B member 1
    Gene ID
    949, 37999904
    UniProt
    Q8WTV0
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Lipid Metabolism, SARS-CoV-2 Protein Interactome
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