Influenza A H1N1 antibody

Details for Product No. ABIN500702
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Antigen
Reactivity
Influenza A Virus H1N1
(16), (5), (4)
Host
Rabbit
(13), (9), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(4), (4), (2)
Application
Enzyme Immunoassay (EIA)
(12), (11), (8), (7), (4), (3), (1), (1), (1)
Pubmed 1 reference available
Quantity 0.1 mg
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
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Catalog No. ABIN500702
401.50 $
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Immunogen NS1 antibody was raised against a synthetic peptide from the Seasonal Influenza NS1 protein.
Isotype IgG
Purification Peptide affinity chromatography
Target Type Virus
Background Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA. In early 2009, a novel swine-origin influenza A (H1N1) virus (S-OIV) was identified in specimens obtained from patients in Mexico and the United States. One of the less studied proteins encoded by, but not incorporated in, the influenza virus is the nonstructural protein (NS) 1. NS1 counters cellular antiviral activities and acts as a virulence factor. It can bind to double-stranded RNA and sequester it from 2'-5' OAS, preventing the activation of the RNAse L, which normally acts to degrade RNA and prevent virus replication. NS1 also binds to and inhibits the anti-viral protein kinase PKR. This antibody is specific for the seasonal H1N1 influenza NS1 and will not recognize the corresponding NS1 sequence from the Swine-Origin H1N1 influenza (A/California/04/2009 (H1N1)).Synonyms: Seasonal Flu H1N1
UniProt A4U724
Application Notes ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Buffer PBS containing 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Background publications Thompson, Shay, Weintraub et al.: "Mortality associated with influenza and respiratory syncytial virus in the United States." in: JAMA : the journal of the American Medical Association, Vol. 289, Issue 2, pp. 179-86, 2003 (PubMed).

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