Orexin B antibody (AA 70-97) (Alexa Fluor 680)

Catalog No. ABIN5008045

Product Details anti-Orexin B Antibody (Alexa Fluor 680)

Target: Orexin B (OXB)

Binding Specificity: AA 70-97

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Orexin B antibody is conjugated to Alexa Fluor 680

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Orexin B

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Orexin B

Target: Orexin B (OXB)

Alternative Name: Orexin B (OXB Products)

Synonyms: PPOX antibody, hypocretin antibody, hypocretin neuropeptide precursor antibody, Hcrt antibody, HCRT antibody

Background:

Synonyms: OX, PPOX, NRCLP1, Orexin, Hypocretin, Hcrt, PPORX

Background: Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Orexin-A binds to both OX1R and OX2R with a high affinity, whereas orexin-B binds only to OX2R with a similar high affinity.

Gene ID: 3060

UniProt: O43612

Pathways: Synaptic Membrane, Feeding Behaviour