DCAF12 antibody (C-Term)

Catalog No. ABIN500873

Product Details anti-DCAF12 Antibody

Target: DCAF12 (DDB1 and CUL4 Associated Factor 12 (DCAF12))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Chicken

Clonality: Polyclonal

Conjugate: This DCAF12 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects DCAF12.

Purification: Peptide affinity chromatography

Immunogen: TCC52 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human TCC52.

Isotype: IgG

Application Details

Application Notes: ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for DCAF12

Target: DCAF12 (DDB1 and CUL4 Associated Factor 12 (DCAF12))

Alternative Name: DCAF12 (DCAF12 Products)

Synonyms: CT102 antibody, KIAA1892 antibody, TCC52 antibody, WDR40A antibody, 1500001L20Rik antibody, 5830424K06Rik antibody, AA420338 antibody, AI851081 antibody, Wdr40a antibody, wdr40a antibody, wu:fb93d04 antibody, zgc:154031 antibody, wdr40b antibody, dcaf12 antibody, wdr40a-a antibody, DDB1 and CUL4 associated factor 12 antibody, DDB1 and CUL4 associated factor 12 L homeolog antibody, DCAF12 antibody, Dcaf12 antibody, dcaf12 antibody, dcaf12.L antibody

Background: Cancer-testis (CT) antigens are a type of antigen whose expression is highly restricted, primarily in normal testis, but aberrantly in different tumor types. Their immunogenicity in cancer patients makes them prime targets for immunotherapy of human tumors. One such CT antigen is TCC52, a novel centrosomal protein. TCC52 is a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates. The normal biological function of this protein is not known at this time.Synonyms: Centrosome-related protein TCC52, DDB1- and CUL4-associated factor 12, KIAA1892, TCC52, Testis cancer centrosome-related protein, WD repeat-containing protein 40A, WDR40A

Gene ID: 25853

NCBI Accession: NP_056212