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TLR1 antibody (Center)

TLR1 Reactivity: Human WB, IF, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN500938
  • Target See all TLR1 Antibodies
    TLR1 (Toll-Like Receptor 1 (TLR1))
    Binding Specificity
    • 16
    • 11
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reactivity
    • 74
    • 49
    • 29
    • 4
    • 4
    • 1
    Human
    Host
    • 73
    • 15
    • 2
    Rabbit
    Clonality
    • 76
    • 14
    Polyclonal
    Conjugate
    • 37
    • 14
    • 10
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TLR1 antibody is un-conjugated
    Application
    • 69
    • 37
    • 32
    • 29
    • 15
    • 13
    • 13
    • 9
    • 8
    • 8
    • 6
    • 5
    • 4
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Cross-Reactivity (Details)
    Species reactivity (tested):Human
    Purification
    Ion exchange chromatography
    Immunogen
    TLR1 antibody was raised against a peptide corresponding to 17 amino acids near the center of human TLR1.
    Isotype
    IgG
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  • Application Notes
    ELISA. Western blot: 1 to 2 μg/mL. Immunoflourescence.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    TLR1 (Toll-Like Receptor 1 (TLR1))
    Alternative Name
    CD281 / TLR1 (TLR1 Products)
    Synonyms
    CD281 antibody, TIL antibody, TIL. LPRS5 antibody, rsc786 antibody, toll like receptor 1 antibody, toll-like receptor 1 antibody, TLR1 antibody, Tlr1 antibody
    Background
    Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (4,5) so the organism can respond to potential infection. TLR1 is co-expressed with TLR2 on myeloid cells of the innate immune systems in lymphoid tissue such as monocytes and dendritic cells (6) where they form heterodimers that can recognize triacylated lipoproteins (7).Synonyms: KIAA0012, TIL, Toll-like receptor 1, Toll/interleukin-1 receptor-like protein
    Pathways
    TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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