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TOLLIP antibody (Center)

TOLLIP Reactivity: Human, Mouse, Rat WB, IF, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN501008
  • Target See all TOLLIP Antibodies
    TOLLIP (Toll Interacting Protein (TOLLIP))
    Binding Specificity
    • 15
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reactivity
    • 41
    • 30
    • 20
    • 17
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 46
    • 11
    • 1
    Rabbit
    Clonality
    • 49
    • 10
    Polyclonal
    Conjugate
    • 34
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This TOLLIP antibody is un-conjugated
    Application
    • 31
    • 18
    • 13
    • 13
    • 12
    • 8
    • 8
    • 7
    • 6
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detecs TOLLIP at Center.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, Mouse, Rat
    Purification
    Peptide Affinity Chromatography
    Immunogen
    Human TOLLIP (Intermediate Domain) Peptide: A 16 amino acid peptide from near the center of Human TOLLIP.
    Isotype
    IgG
    Top Product
    Discover our top product TOLLIP Primary Antibody
  • Application Notes
    ELISA. Western blot: 1 μg/mL. Immunoflourescence. Positive Controls: Rat Brain Tissue Lysate, THP-1 Cell Lysate.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C.
  • Target
    TOLLIP (Toll Interacting Protein (TOLLIP))
    Alternative Name
    TOLLIP (TOLLIP Products)
    Synonyms
    IL-1RAcPIP antibody, 4930403G24Rik antibody, 4931428G15Rik antibody, fk22a02 antibody, im:7145391 antibody, wu:fk22a02 antibody, zgc:76985 antibody, TOLLIP antibody, GB17961 antibody, tollip antibody, tollip1 antibody, tollipa antibody, TOLIP antibody, toll interacting protein antibody, toll-interacting protein antibody, toll-interacting protein-like antibody, toll interacting protein L homeolog antibody, toll interacting protein S homeolog antibody, Toll-interleukine I receptor interacting protein I antibody, TOLLIP antibody, Tollip antibody, tollip antibody, LOC552034 antibody, LOC100169858 antibody, tollip.L antibody, tollip.S antibody, LOC100136122 antibody
    Background
    Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1,2). The TLRs act through adaptor molecules to activate various kinases and transcription factors (3) so the organism can respond to potential infection. These adaptor molecules include TOLLIP, MyD88, and TRIF. TOLLIP associates directly with TLR2 and TLR 4, acting as an inhibitor to TLR activation (4). This negative regulation of TLR signaling may serve to limit the production of proinflammatory mediators during infection and inflammation.Synonyms: Toll-interacting protein
    Gene ID
    54472
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