WNT10B antibody (Center)

Catalog No. ABIN501124

Product Details anti-WNT10B Antibody

Target: WNT10B (Wingless-Type MMTV Integration Site Family, Member 10B (WNT10B))

Binding Specificity: Center

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WNT10B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody detects WNT10B. The Wnt10b antibody will not cross-react with Wnt10a.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography

Immunogen: Wnt10b antibody was raised against a 15 amino acid peptide from near the center of human Wnt10b.

Isotype: IgG

Application Details

Application Notes: ELISA. Western blot. Immunohistochemistry on paraffin sections: 2 - 4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Target Details for WNT10B

Target: WNT10B (Wingless-Type MMTV Integration Site Family, Member 10B (WNT10B))

Alternative Name: WNT10B (WNT10B Products)

Synonyms: WNT10B antibody, Xwnt-10b antibody, Xwnt10b antibody, wnt-12 antibody, Wnt12 antibody, SHFM6 antibody, WNT-12 antibody, Xwnt-10 antibody, wnt10 antibody, wnt10-A antibody, Zwnt[d] antibody, wnt10br antibody, wnt[d] antibody, Wnt family member 10B antibody, wingless-type MMTV integration site family, member 10B antibody, Wnt family member 10B S homeolog antibody, wingless-type MMTV integration site family, member 10b antibody, WNT10B antibody, wnt10b antibody, Wnt10b antibody, wnt10b.S antibody

Background: Wnt10b is a member of the Wnt family, a gene family that encodes secreted signaling proteins that play crucial roles in normal development such as regulation of cell fate and patterning during embryogenesis as well as neoplastic transformation. Wnt10b is found in the mouse mammary tumor virus insertion site where it is activated and causes mammary tumors. Elevated levels of Wnt10b have also been detected in human breast carcinomas. Wnt10b is known to be involved in adipogenesis, maintaining the preadipocyte in an undifferentiated state. More recently, Wnt10b has been shown to promote epithelial cell differentiation and hair shaft growth, demonstrating that Wnt10b has multiple roles in cell growth and differentiation. Two isoforms of Wnt10b are known to exist, this antibody will only recognize the longer isoform.Synonyms: Protein Wnt-10b, WNT12, Wnt-12

Gene ID: 7480

NCBI Accession: NP_003385

Pathways: WNT Signaling, Skeletal Muscle Fiber Development