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Atrophin 1 antibody (N-Term)

ATN1 Reactivity: Human, Mouse, Rat, Rabbit, Cow, Dog, Horse, Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN501239
  • Target See all Atrophin 1 (ATN1) Antibodies
    Atrophin 1 (ATN1)
    Binding Specificity
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 22
    • 18
    • 9
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Human, Mouse, Rat, Rabbit, Cow, Dog, Horse, Pig
    Host
    • 20
    • 2
    • 1
    Rabbit
    Clonality
    • 21
    • 2
    Polyclonal
    Conjugate
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Atrophin 1 antibody is un-conjugated
    Application
    • 15
    • 6
    • 5
    • 4
    • 4
    • 2
    Western Blotting (WB)
    Sequence
    VSTSSSDGKA EKSRQTAKKA RVEEASTPKV NKQGRSEEIS ESESEETNAP
    Predicted Reactivity
    Cow: 93%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 100%, Rat: 93%
    Characteristics
    This is a rabbit polyclonal antibody against ATN1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human ATN1
    Top Product
    Discover our top product ATN1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 1190 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Atrophin 1 (ATN1)
    Alternative Name
    ATN1 (ATN1 Products)
    Synonyms
    B37 antibody, D12S755E antibody, DRPLA antibody, HRS antibody, NOD antibody, Atr1 antibody, Drpla antibody, atrophin-1 antibody, RERE antibody, ATN1 antibody, atrophin 1 antibody, ATN1 antibody, Atn1 antibody
    Background
    Dentatorubral pallidoluysian atrophy is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion of a trinucleotide repeat within ATN1. The protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein.Dentatorubral pallidoluysian atrophy is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion of a trinucleotide repeat within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein.
    Alias Symbols: B37, D12S755E, DRPLA, NOD, HRS
    Protein Interaction Partner: WWOX, Dlg4, SIAH1, HINFP, LRP2, RBFOX1, EFEMP2, NOC2L, RCHY1, ZMYND8, RBFOX2, KAT6B, SSPO, RAD54L2, ZSWIM8, WDR5, WWP2, WWP1, RBPMS, SPAG5, FBLN5, BAIAP2, PSME3, CBFA2T2, CHRD, NCK2, LTBP4, RBM10, KAT6A, BAG6, PRRC2A, TRIP6, TEP1, SLIT1, SIAH2, PSMA3, PLS
    Protein Size: 1190
    Molecular Weight
    125 kDa
    Gene ID
    1822
    NCBI Accession
    NM_001940, NP_001931
    UniProt
    P54259
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