KCNJ5 antibody (N-Term)

Catalog No. ABIN501366

Product Details anti-KCNJ5 Antibody

Target: KCNJ5 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 5 (KCNJ5))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Pig, Rabbit, Horse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNJ5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AGDSRNAMNQ DMEIGVTPWD PKKIPKQARD YVPIATDRTR LLAEGKKPRQ

Predicted Reactivity: Cow: 93%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against KCNJ5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KCNJ5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 419 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for KCNJ5

Target: KCNJ5 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 5 (KCNJ5))

Alternative Name: KCNJ5 (KCNJ5 Products)

Synonyms: CIR antibody, GIRK4 antibody, KATP1 antibody, KIR3.4 antibody, LQT13 antibody, Kir3.4 antibody, GIRK-4 antibody, KATP-1 antibody, potassium voltage-gated channel subfamily J member 5 antibody, potassium inwardly-rectifying channel, subfamily J, member 5 antibody, KCNJ5 antibody, Kcnj5 antibody

Background: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. KCNJ5 is an integral membrane protein and inward-rectifier type potassium channel. KCNJ5, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins. It may associate with two other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex.Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins. It may associate with two other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex. Sequence Note: The sequence U52154.1 is a chimeric mRNA clone. Only the potassium inwardly-rectifying channel, subfamily J, member 5 region was propagated into this RefSeq record. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CIR, GIRK4, KATP1, KIR3.4, LQT13
Protein Interaction Partner: KCNJ5, KCNJ3, DRD4, DRD2, ADRB2,
Protein Size: 419

Molecular Weight: 48 kDa

Gene ID: 3762

NCBI Accession: NM_000890, NP_000881

UniProt: P48544

Pathways: Notch Signaling