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Calcium Channel, Voltage-Dependent, beta 2 Subunit (CACNB2) antibody

Antigen

Calcium Channel, Voltage-Dependent, beta 2 Subunit (CACNB2)

Synonyms MYSB, CAVB2, CACNLB2, FLJ23743, Cchb2, AW060387, Cavbeta2, MGC129334, MGC129335, Cacnlb2, CACNB2, CAB2, Cacnb2, DKFZp468H0713
Clonality Polyclonal
Host
Alternatives

Rabbit

Reactivity
Alternatives

Cow (Bovine), Human, Mouse (Murine), Rat (Rattus), Dog (Canine), Rabbit, Xenopus laevis

Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB)
1 reference available
Catalog no. ABIN501436
Quantity 50 µg  (Variants)
Price 317.90 $   Plus shipping costs $45.00
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Additional Information

Alternative name CACNB2
Gene ID CACNB2
UniProt A6PVM7
Immunogen The immunogen for anti-CACNB2 antibody: synthetic peptide directed towards the middle region of human CACNB2
Sequence DACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPL SPTLASNSQG
Cross-Reactivity Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rabbit, Rat (Rattus)
Format Lyophilized
Reconstitution Add 50 µl of distilled water. Final anti-CACNB2 antibody concentration is 1 mg/ml.
Description CACNB2 belongs to the calcium channel beta subunit family.The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.Defects in CACNB2 are the cause of Brugada syndrome type 4 (BRS4).
Characteristics Antigen Size: 608 amino acids
Molecular Weight 68kDa

Application Details

Application Notes WB Suggested Anti-CACNB2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: MCF7 cell lysate.
Purification Affinity Purified
Buffer PBS
Storage (Long Term) For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Storage (Short Term) Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.
Research Area Neurology
Restrictions For Research Use only

Publications

Product Uhl, Liu, Drgon et al.: "Molecular genetics of successful smoking cessation: convergent genome-wide association study results." in: Archives of general psychiatry, Vol. 65, Issue 6, pp. 683-93, 2008 (PubMed).

Alternatives

Alternatives for antigen "Calcium Channel, Voltage-Dependent, beta 2 Subunit (CACNB2)", type "Antibodies"
Hosts Rabbit (60), Mouse (9), Goat (3)
Reactivities Human (57), Mouse (Murine) (32), Rat (Rattus) (32), Dog (Canine) (24), Chicken (20), Horse (Equine) (18), Cow (Bovine) (9), Rabbit (7), Xenopus laevis (1)
Applications Western Blotting (WB) (52), Immunofluorescence (IF) (16), ELISA (15), Immunohistochemistry (IHC) (6), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (5), Immunoprecipitation (IP) (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunocytochemistry (ICC) (2), Immunostaining (ISt) (2), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Fixed) (IHC (fx)) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
Conjugates Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
Epitopes C-Term (7), Internal Region (7), N-Term (2), AA 189-205 (1), AA 213-301 (1), AA 565-579 (1), C-Term,AA 565-579 (1), Center (1)