Calcium Channel, Voltage-Dependent, beta 2 Subunit (CACNB2) (Middle Region) antibody

Details for Product No. ABIN501437
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Antigen
Synonyms CACNLB2, CAVB2, MYSB, AW060387, CAB2, Cavbeta2, Cchb2, Cacnlb2, Cacnb2, CACNB2
Epitope
Middle Region
(12), (8), (8), (7), (4), (3), (3), (2)
Reactivity
Rabbit, Mouse (Murine), Rat (Rattus), Cow (Bovine), Human
(62), (30), (28), (18), (14), (8), (7), (2), (2)
Host
Rabbit
(58), (16), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(63), (16), (10), (6), (4), (3), (2), (1), (1), (1)
Pubmed 1 reference available
Catalog no. ABIN501437
Quantity 50 µg
Price
289.00 $   Plus shipping costs $45.00
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Immunogen Synthetic peptide directed towards the middle region of human CACNB2
Sequence HLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTL ASNSQGSQGD
Predicted Reactivity Human : 100 %, Mouse : 90 %, Rat : 90 %, Bovine : 80 %, Guinea pig : 80 %, Pig : 70 %
Characteristics This is a rabbit polyclonal antibody against CACNB2. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name CACNB2
Background CACNB2 contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. Defects in CACNB2 are the cause of Brugada syndrome type 4 (BRS4).
Molecular Weight 68 kDa
Gene ID 783
NCBI Accession NM_201590, NP_963884
UniProt Q08289
Research Area Neurology
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 605 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Background publications Uhl, Liu, Drgon et al.: "Molecular genetics of successful smoking cessation: convergent genome-wide association study results." in: Archives of general psychiatry, Vol. 65, Issue 6, pp. 683-93, 2008 (PubMed).

Hosts (58), (16), (3)
Reactivities (62), (30), (28), (18), (14), (8), (7), (2), (2)
Applications (63), (16), (10), (6), (4), (3), (2), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (12), (8), (8), (7), (4), (3), (3), (2)
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