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Calcium Channel, Voltage-Dependent, beta 2 Subunit (CACNB2) antibody

Antigen

Calcium Channel, Voltage-Dependent, beta 2 Subunit (CACNB2)
Synonyms MYSB, CAVB2, CACNLB2, FLJ23743, Cchb2, AW060387, Cavbeta2, MGC129334, MGC129335, Cacnlb2, CACNB2, CAB2, Cacnb2, DKFZp468H0713
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Cow (Bovine), Human, Mouse (Murine), Rat (Rattus), Rabbit
Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB)
1 reference available
Catalog no. ABIN501437
Quantity 50 µg  (Variants)
Price 317.90 $   Plus shipping costs $45.00
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anti-Calcium Channel, Voltage-Dependent, beta 2 Subunit (CACNB2) antibody

Additional Information
Application Details Publications Images Alternatives Variants back to top

Alternative name CACNB2
Gene ID CACNB2
UniProt Q08289
Immunogen The immunogen for anti-CACNB2 antibody: synthetic peptide directed towards the middle region of human CACNB2
Sequence HLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTL ASNSQGSQGD
Cross-Reactivity Cow (Bovine), Human, Mouse (Murine), Rabbit, Rat (Rattus)
Format Lyophilized
Reconstitution Add 50 µl of distilled water. Final anti-CACNB2 antibody concentration is 1 mg/ml.
Description CACNB2 contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. Defects in CACNB2 are the cause of Brugada syndrome type 4 (BRS4).
Characteristics Antigen Size: 605 amino acids
Molecular Weight 68kDa

Application Details
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Application Notes WB Suggested Anti-CACNB2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Human heart.
Purification Affinity Purified
Buffer PBS
Storage (Long Term) For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Storage (Short Term) Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.
Research Area Neurology
Restrictions For Research Use only

Publications
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Product Uhl, Liu, Drgon et al.: "Molecular genetics of successful smoking cessation: convergent genome-wide association study results." in: Archives of general psychiatry, Vol. 65, Issue 6, pp. 683-93, 2008 (PubMed).

Alternatives
Application Details Publications Images Variants back to top

Alternatives for antigen "Calcium Channel, Voltage-Dependent, beta 2 Subunit (CACNB2)", type "Antibodies"
Hosts Rabbit (60), Mouse (9), Goat (3)
Reactivities Human (56), Mouse (Murine) (29), Rat (Rattus) (29), Dog (Canine) (24), Chicken (20), Horse (Equine) (18), Cow (Bovine) (9), Rabbit (7), Xenopus laevis (2)
Applications Western Blotting (WB) (52), Immunofluorescence (IF) (16), ELISA (15), Immunohistochemistry (IHC) (7), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (5), Immunoprecipitation (IP) (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunostaining (ISt) (2), Immunocytochemistry (ICC) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Fixed) (IHC (fx)) (1)
Conjugates Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
Epitopes C-Term (7), Internal Region (7), AA 189-205 (2), AA 565-579 (2), Center (2), N-Term (2), AA 213-301 (1), C-Term,AA 565-579 (1)