Homeobox A3 (HOXA3) (Middle Region) antibody

Details for Product No. ABIN501500
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Antigen
Synonyms hox1e, hoxa-3, hoxa3a, MGC52707, HOXA3, hoxa3, hox1, cb332, fa10d03, wu:fa10d03, HOX1, HOX1E, Hox-1.5, Mo-10, RGD1561431
Epitope
Middle Region
(21), (8), (7), (2), (2), (2), (2), (1)
Reactivity
Rabbit, Mouse (Murine), Rat (Rattus), Cow (Bovine), Dog (Canine), Human
(30), (25), (16), (13), (13), (12), (1), (1), (1)
Host
Rabbit
(39), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(31), (13), (10), (10), (8), (7), (2), (2), (1)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN501500
289.00 $
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Immunogen Synthetic peptide directed towards the middle region of human HOXA3
Sequence PPQKRYTAAG AGAGGTPDYD PHAHGLQGNG SYGTPHIQGS PVFVGGSYVE
Predicted Reactivity Human : 100 %, Pig : 100 %, Rabbit : 90 %, Guinea pig : 90 %, Dog : 80 %
Characteristics This is a rabbit polyclonal antibody against HOXA3. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name HOXA3
Background In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA3 gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Three transcript variants encoding two different isoforms have been found for this gene. In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Three transcript variants encoding two different isoforms have been found for this gene.
Molecular Weight 46 kDa
Gene ID 3200
NCBI Accession NM_030661, NP_109377
UniProt O43365
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 443 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Background publications Wissmüller, Kosian, Wolf et al.: "The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors." in: Nucleic acids research, Vol. 34, Issue 6, pp. 1735-44, 2006 (PubMed).

Validation Images
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