CACNB2 antibody (N-Term)

Catalog No. ABIN501591

Product Details anti-CACNB2 Antibody

Target: CACNB2 (Calcium Channel, Voltage-Dependent, beta 2 Subunit (CACNB2))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CACNB2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: IQMELLENVA PAGALGAAAQ SYGKGARRKN RFKGSDGSTS SDTTSNSFVR

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against CACNB2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the n terminal region of human CACNB2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 660 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CACNB2

Target: CACNB2 (Calcium Channel, Voltage-Dependent, beta 2 Subunit (CACNB2))

Alternative Name: CACNB2 (CACNB2 Products)

Synonyms: CACNLB2 antibody, CAVB2 antibody, MYSB antibody, AW060387 antibody, CAB2 antibody, Cavbeta2 antibody, Cchb2 antibody, Cacnlb2 antibody, Cacnb2 antibody, CACNB2 antibody, CACNB2.2 antibody, cacnb2a antibody, im:7141271 antibody, si:dkey-32m20.2 antibody, calcium voltage-gated channel auxiliary subunit beta 2 antibody, calcium channel, voltage-dependent, beta 2 subunit antibody, calcium channel, voltage-dependent, beta 2b antibody, CACNB2 antibody, Cacnb2 antibody, cacnb2b antibody

Background: CACNB2 belongs to the calcium channel beta subunit family.The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.Defects in CACNB2 are the cause of Brugada syndrome type 4 (BRS4).
Alias Symbols: CACNLB2, FLJ23743, MYSB, CAVB2
Protein Interaction Partner: REM1, PRKACA,
Protein Size: 660

Molecular Weight: 73 kDa

Gene ID: 783

NCBI Accession: NM_201596, NP_963890

UniProt: Q08289

Pathways: Skeletal Muscle Fiber Development