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IRF4 antibody (Interferon Regulatory Factor 4) (Middle Region)

Details for Product anti-IRF4 Antibody No. ABIN501643, Supplier: Login to see New
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Antigen
Synonyms IRF4, irf4, LSIRF, MUM1, NF-EM5, AI385587, IRF-4, Spip, si:ch73-170d1.2
Alternatives
Epitope
Middle Region
(32), (8), (8), (7), (6), (6), (5), (5), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Chicken, Human
(145), (48), (19), (2), (2), (2), (2), (2), (1)
Host
Rabbit
(96), (24), (15), (13), (2)
Clonality
Polyclonal
Conjugate
This IRF4 antibody is un-conjugated
(4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(119), (53), (36), (30), (22), (12), (8), (5), (5), (5), (4), (3), (1)
Pubmed 1 reference available
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Quantity 50 μg
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Immunogen Synthetic peptide directed towards the middle region of human IRF4
Blocking Peptide Blocking peptide for this product available: ABIN978604
Sequence TAHVEPLLAR QLYYFAQQNS GHFLRGYDLP EHISNPEDYH RSIRHSSIQE
Predicted Reactivity Chicken : 100 %, Dog : 100 %, Human : 100 %, Guinea pig : 90 %, Horse : 90 %, Rabbit : 80 %, Pig : 80 %
Characteristics This is a rabbit polyclonal antibody against IRF4. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name IRF4 (IRF4 Antibody Abstract)
Background IRF4 is a transcriptional activator. It binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter.It also binds the immunoglobulin lambda light chain enhancer, together with PU.1. IRF4 probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells.
Molecular Weight 52 kDa
Gene ID 3662
NCBI Accession NM_002460, NP_002451
UniProt Q15306
Pathways TCR Signaling
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 451 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-IRF4 antibody (Interferon Regulatory Factor 4) (Middle Region) (ABIN501643) WB Suggested Anti-IRF4 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: ...
Western Blotting (WB) image for anti-IRF4 antibody (Interferon Regulatory Factor 4) (Middle Region) (ABIN501643) Host: Rabbit
Target Name: IRF4
Sample Tissue: Human Fetal Muscle
...
Product cited in: Han, Kraft, Nan et al.: "A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation." in: PLoS genetics, Vol. 4, Issue 5, pp. e1000074, 2008 (PubMed).

Catalog No. ABIN501643
$289.00
Plus shipping costs $45.00

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