Eomesodermin (EOMES) (Middle Region) antibody

Details for Product No. ABIN501713
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Antigen
Synonyms TBR2, xeomes, EOMES, tbr2, eom, eomes
Epitope
Middle Region
(11), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine), Human
(42), (21), (14), (12), (12), (1)
Host
Rabbit
(32), (8), (2), (2), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(35), (18), (10), (7), (4), (4), (2), (1)
Pubmed 1 reference available
Catalog no. ABIN501713
Quantity 50 µg
Price
289.00 $   Plus shipping costs $45.00
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Immunogen Synthetic peptide directed towards the middle region of human EOMES
Sequence YTSACKRRRLSPSNSSNENSPSIKCEDINAEEYSKDTSKG MGGYYAFYTT
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Human : 100 %, Pig : 100 %, Rabbit : 100 %, Chicken : 90 %, Guinea pig : 90 %, Horse : 90 %, Mouse : 90 %
Characteristics This is a rabbit polyclonal antibody against EOMES. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name EOMES
Background EOMES is a member of a conserved protein family that shares a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similiar gene disrupted in mice is shown to be essential
Molecular Weight 73 kDa
Gene ID 8320
NCBI Accession NM_005442, NP_005433
UniProt O95936
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 686 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Eomesodermin (EOMES) (Middle Region) antibody WB Suggested Anti-EOMES Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: NCI-H226 cell lysate
Background publications Baala, Briault, Etchevers et al.: "Homozygous silencing of T-box transcription factor EOMES leads to microcephaly with polymicrogyria and corpus callosum agenesis." in: Nature genetics, Vol. 39, Issue 4, pp. 454-6, 2007 (PubMed).

Hosts (32), (8), (2), (2), (1)
Reactivities (42), (21), (14), (12), (12), (1)
Applications (35), (18), (10), (7), (4), (4), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (11), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1)
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