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Glucagon antibody (Middle Region)

GCG Reactivity: Human, Rat, Mouse, Cow, Dog, Sheep, Guinea Pig, Rabbit, Horse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN502203
  • Target See all Glucagon (GCG) Antibodies
    Glucagon (GCG)
    Binding Specificity
    • 16
    • 14
    • 11
    • 7
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 117
    • 46
    • 41
    • 12
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Rat, Mouse, Cow, Dog, Sheep, Guinea Pig, Rabbit, Horse
    Host
    • 75
    • 30
    • 14
    • 4
    • 1
    Rabbit
    Clonality
    • 82
    • 41
    Polyclonal
    Conjugate
    • 75
    • 10
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Glucagon antibody is un-conjugated
    Application
    • 52
    • 50
    • 28
    • 16
    • 14
    • 13
    • 13
    • 12
    • 12
    • 11
    • 10
    • 9
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    VSSYLEGQAA KEFIAWLVKG RGRRDFPEEV AIVEELGRRH ADGSFSDEMN
    Predicted Reactivity
    Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 93%
    Characteristics
    This is a rabbit polyclonal antibody against GCG. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human GCG
    Top Product
    Discover our top product GCG Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 180 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Glucagon (GCG)
    Alternative Name
    GCG (GCG Products)
    Synonyms
    GLP1 antibody, GLP2 antibody, GRPP antibody, GLP-1 antibody, Glu antibody, PPG antibody, GCG antibody, gcg-A antibody, gcg1 antibody, glucagon antibody, glucagon L homeolog antibody, GCG antibody, Gcg antibody, gcg.L antibody
    Background
    GCG is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a li
    Alias Symbols: GLP1, GLP2, GRPP
    Protein Interaction Partner: ARRB2, GLP1R, GLP2R, MEP1B, MEP1A, GCGR, CTSL, CPE,
    Protein Size: 180
    Molecular Weight
    4 kDa
    Gene ID
    2641
    NCBI Accession
    NM_002054, NP_002045
    UniProt
    P01275
    Pathways
    Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Negative Regulation of intrinsic apoptotic Signaling
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