F-Box Protein 3 (FBXO3) (N-Term) antibody

Details for Product No. ABIN502350
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Antigen
Synonyms zgc:112485, DKFZp459H187, FBA, FBX3, 1200002G09Rik, 1700026K02Rik, AI046358, Fba
Epitope
N-Term
(10), (8), (5), (2), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Cow (Bovine), Dog (Canine), Human
(21), (4), (4), (2)
Host
Rabbit
(20), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(21), (12), (11), (2), (1), (1)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN502350
289.00 $
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Immunogen Synthetic peptide directed towards the N terminal of human FBXO3
Sequence NCCYVSRRLS QLSSHDPLWR RHCKKYWLIS EEEKTQKNQC WKSLFIDTYS
Predicted Reactivity Dog : 100 %, Horse : 100 %, Human : 100 %, Pig : 100 %, Chicken : 90 %, Mouse : 90 %
Characteristics This is a rabbit polyclonal antibody against FBXO3. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name FBXO3
Background FBXO3 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXO3 belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants diverging at the 3' end. This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants diverging at the 3' end.
Molecular Weight 47 kDa
Gene ID 26273
NCBI Accession NP_208385, NM_033406
UniProt Q9UK99
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 415 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Background publications Ilyin, Rialland, Pigeon et al.: "cDNA cloning and expression analysis of new members of the mammalian F-box protein family." in: Genomics, Vol. 67, Issue 1, pp. 40-7, 2000 (PubMed).

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