GCDH antibody (N-Term)

Catalog No. ABIN502403

Product Details anti-GCDH Antibody

Target: GCDH (Glutaryl-CoA Dehydrogenase (GCDH))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Rabbit, Horse, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GCDH antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SLVMHPIYAY GSEEQRQKYL PQLAKGELLG CFGLTEPNSG SDPSSMETRA

Predicted Reactivity: Cow: 92%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against GCDH. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GCDH

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 438 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GCDH

Target: GCDH (Glutaryl-CoA Dehydrogenase (GCDH))

Alternative Name: GCDH (GCDH Products)

Synonyms: ACAD5 antibody, GCD antibody, zgc:56505 antibody, zgc:77704 antibody, 9030411L18 antibody, AI266902 antibody, D17825 antibody, glutaryl-CoA dehydrogenase antibody, glutaryl-CoA dehydrogenase a antibody, glutaryl-Coenzyme A dehydrogenase antibody, GCDH antibody, Gcdh antibody, gcdha antibody

Background: GCDH belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits.Alternatively spliced transcript variants encoding different isoforms have been identified.The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: ACAD5, GCD
Protein Interaction Partner: UBC, FBXO6, ADRB2, RNF32, EXOC6, ECSIT, MAST1, CDC37, PSEN2, PSEN1, NOS3, APOE, A2M, UBD, MYC, GCDH,
Protein Size: 438

Molecular Weight: 43 kDa

Gene ID: 2639

NCBI Accession: NM_000159, NP_000150

UniProt: Q92947