C-Type Lectin Domain Family 6, Member A (CLEC6A) (AA 70-230) antibody
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- Target See all C-Type Lectin Domain Family 6, Member A (CLEC6A) Antibodies
- C-Type Lectin Domain Family 6, Member A (CLEC6A)
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Binding Specificity
- AA 70-230
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- Un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Cross-Reactivity
- Mouse (Murine)
- Purification
- Protein G Chromatography
- Immunogen
- A partial length recombinant Dectin-2 protein (amino acids 70-230) was used as the immunogen for this antibody.
- Clone
- ABM2H28
- Isotype
- IgG3 kappa
- Top Product
- Discover our top product CLEC6A Primary Antibody
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- Application Notes
- WB: 2-4 μg/mL,FACS: 0.5 μg/10^6 cells, IHC: 5 μg/mL
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- PBS containing 0.05 % BSA, PH 7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- Target
- C-Type Lectin Domain Family 6, Member A (CLEC6A)
- Alternative Name
- Dectin-2 (CLEC6A Products)
- Synonyms
- CLEC4N antibody, CLECSF10 antibody, CLEC6A antibody, C-type lectin domain containing 6A antibody, C-type lectin domain family 6, member A antibody, CLEC6A antibody, Clec6a antibody
- Background
- Dectin-2 (C-type lectin domain family 6 member A) is a type II membrane receptor with an extracellular C-type lectin-like domain fold. Dectin-2 plays an important role in the host defense against C. albicans infection by inducing TH17 cell differentiation. It binds high-mannose carbohydrates in a Ca(2+)-dependent manner. In Dectin-2 glycosylation occurs at Asn131, Asn170. Dectin-2 has 2 isoforms produced by alternative splicing. Dectin-2 is strongly expressed in monocytes and weakly in B-cells and also expressed in spleen, tonsils, lymph node, lungs, leukocytes, dendritic cells and bone marrow.
- Molecular Weight
- 32 kDa
- Gene ID
- 93978
- UniProt
- Q6EIG7
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