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C-Type Lectin Domain Family 6, Member A (CLEC6A) (AA 70-230) antibody

CLEC6A Reactivity: Human WB, IHC, FACS Host: Mouse Monoclonal ABM2H28 unconjugated
Catalog No. ABIN5027146
  • Target See all C-Type Lectin Domain Family 6, Member A (CLEC6A) Antibodies
    C-Type Lectin Domain Family 6, Member A (CLEC6A)
    Binding Specificity
    • 15
    • 8
    • 7
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 70-230
    Reactivity
    • 38
    • 8
    • 2
    • 1
    Human
    Host
    • 36
    • 4
    • 1
    • 1
    • 1
    Mouse
    Clonality
    • 38
    • 5
    Monoclonal
    Conjugate
    • 17
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Un-conjugated
    Application
    • 23
    • 17
    • 13
    • 13
    • 7
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
    Cross-Reactivity
    Mouse (Murine)
    Purification
    Protein G Chromatography
    Immunogen
    A partial length recombinant Dectin-2 protein (amino acids 70-230) was used as the immunogen for this antibody.
    Clone
    ABM2H28
    Isotype
    IgG3 kappa
    Top Product
    Discover our top product CLEC6A Primary Antibody
  • Application Notes
    WB: 2-4 μg/mL,FACS: 0.5 μg/10^6 cells, IHC: 5 μg/mL
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    PBS containing 0.05 % BSA, PH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • Target
    C-Type Lectin Domain Family 6, Member A (CLEC6A)
    Alternative Name
    Dectin-2 (CLEC6A Products)
    Synonyms
    CLEC4N antibody, CLECSF10 antibody, CLEC6A antibody, C-type lectin domain containing 6A antibody, C-type lectin domain family 6, member A antibody, CLEC6A antibody, Clec6a antibody
    Background
    Dectin-2 (C-type lectin domain family 6 member A) is a type II membrane receptor with an extracellular C-type lectin-like domain fold. Dectin-2 plays an important role in the host defense against C. albicans infection by inducing TH17 cell differentiation. It binds high-mannose carbohydrates in a Ca(2+)-dependent manner. In Dectin-2 glycosylation occurs at Asn131, Asn170. Dectin-2 has 2 isoforms produced by alternative splicing. Dectin-2 is strongly expressed in monocytes and weakly in B-cells and also expressed in spleen, tonsils, lymph node, lungs, leukocytes, dendritic cells and bone marrow.
    Molecular Weight
    32 kDa
    Gene ID
    93978
    UniProt
    Q6EIG7
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