TWIST Neighbor antibody (AA 28-257)

Catalog No. ABIN5027613

Product Details anti-TWIST Neighbor Antibody

Target: TWIST Neighbor (TWISTNB)

Binding Specificity: AA 28-257

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TWIST Neighbor antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Protein A Chromatography

Immunogen: A partial length recombinant Twistnb protein (amino acids 28-257) was used as the immunogen for this antibody.

Isotype: IgG

Application Details

Application Notes: WB: 1-2 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Target Details for TWIST Neighbor

Target: TWIST Neighbor (TWISTNB)

Alternative Name: Twistnb (TWISTNB Products)

Background: Twistnb is a DNA-dependent RNA polymerase that catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors through its association with RRN3/TIF-IA may be involved in recruitment of Pol I to rDNA promoters. This protein contains 2 potential nuclear localization signals in the C terminus and shares 72 % sequence identity with the mouse orthologs. Twistnb has highest expression in fetal lung, liver, and kidney, and low expression in all adult tissues.

Molecular Weight: 37 kDa

Gene ID: 221830

UniProt: Q3B726