UBA6 antibody (AA 710-955)

Catalog No. ABIN5027617

Product Details anti-UBA6 Antibody

Target: UBA6 (Ubiquitin-Like Modifier Activating Enzyme 6 (UBA6))

Binding Specificity: AA 710-955

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBA6 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Protein A Chromatography

Immunogen: A partial length recombinant UBE1L2 protein (amino acids 710-955) was used as the immunogen for this antibody.

Isotype: IgG

Application Details

Application Notes: WB: 2-4 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Target Details for UBA6

Target: UBA6 (Ubiquitin-Like Modifier Activating Enzyme 6 (UBA6))

Alternative Name: UBE1L2/MOP-4 (UBA6 Products)

Synonyms: E1-L2 antibody, MOP-4 antibody, UBE1L2 antibody, 4930542H01 antibody, 5730469D23Rik antibody, AU021846 antibody, AW124799 antibody, Ube1l2 antibody, RGD1308324 antibody, ubiquitin like modifier activating enzyme 6 antibody, ubiquitin-like modifier activating enzyme 6 antibody, UBA6 antibody, Uba6 antibody

Background: Uba6/UBE1L2/MOP-4 is an ubiquitin-specific E1 type enzyme, homolog of the ubiquitin-activating enzyme, Uba1, which activates two ubiquitin-like proteins (UBLs), ubiquitin and FAT10. Some recent experiments suggest a testis-specific function of UBE1L2. UBE1L2 forms a thioester with FAT10 and this reaction requires the active-site cysteine of UBE1L2 and the C-terminal diglycine motif of FAT10. It can transfer ubiquitin to Ubc5 and Ubc13, suggesting its specialized role in ubiquitination reactions.

Molecular Weight: 115 kDa

Gene ID: 55236

UniProt: A0AVT1