FOXN4 antibody (C-Term)

Catalog No. ABIN502898

Product Details anti-FOXN4 Antibody

Target: FOXN4 (Forkhead Box N4 (FOXN4))

Binding Specificity: C-Term

Reactivity: Human, Dog, Mouse, Cow, Pig, Zebrafish (Danio rerio), Horse, Rabbit, Rat, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXN4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: HHQVQPQAHL APDSPAPAQT PPLHALPDLS PSPLPHPAMG RAPVDFINIS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 93%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against FOXN4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human FOXN4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 517 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FOXN4

Target: FOXN4 (Forkhead Box N4 (FOXN4))

Alternative Name: FOXN4 (FOXN4 Products)

Synonyms: whn antibody, whna antibody, forkhead box N4 antibody, forkhead box N4 S homeolog antibody, FOXN4 antibody, foxn4 antibody, Foxn4 antibody, foxn4.S antibody

Background: Members of the winged-helix/forkhead family of transcription factors, such as FOXN4, are characterized by a 110-amino acid DNA-binding domain that can fold into a variant of the helix-turn-helix motif consisting of 3 alpha helices flanked by 2 large loops or wings. These transcription factors are involved in a variety of biologic processes as key regulators in development and metabolism.Members of the winged-helix/forkhead family of transcription factors, such as FOXN4, are characterized by a 110-amino acid DNA-binding domain that can fold into a variant of the helix-turn-helix motif consisting of 3 alpha helices flanked by 2 large loops or wings. These transcription factors are involved in a variety of biologic processes as key regulators in development and metabolism (Li et al., 2004 [PubMed 15363391]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-178 BC146825.1 2-179 179-191 AK131519.1 179-191 192-500 BC146825.1 193-501 501-1569 AF425596.1 276-1344 1570-3350 BC146825.1 1571-3351 3351-3356 AA421288.1 1-6 c
Alias Symbols: FLJ35967
Protein Size: 517

Molecular Weight: 56 kDa

Gene ID: 121643

NCBI Accession: NM_213596, NP_998761

UniProt: Q96NZ1