CNN1 antibody (N-Term)

Catalog No. ABIN502911

Product Details anti-CNN1 Antibody

Target: CNN1 (Calponin 1 (CNN1))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Pig, Sheep, Zebrafish (Danio rerio), Cow, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNN1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MSSAHFNRGP AYGLSAEVKN KLAQKYDHQR EQELREWIEG VTGRRIGNNF

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against CNN1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CNN1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 297 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CNN1

Target: CNN1 (Calponin 1 (CNN1))

Alternative Name: CNN1 (CNN1 Products)

Synonyms: CN antibody, CnnI antibody, SMCC antibody, Sm-Calp antibody, XclpH3 antibody, clpH3 antibody, cnn2 antibody, calponin 1 antibody, calponin 1, basic, smooth muscle L homeolog antibody, cnn1 antibody, Cnn1 antibody, CNN1 antibody, cnn1.L antibody

Background: CNN1 is a thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
Alias Symbols: SMCC, Sm-Calp
Protein Interaction Partner: ADRB2, TUBB, DNMBP, UBC, TPM1, TNNC1, CALM1, TPM3, PRKCE, FYN, ACTA1, MYO1A,
Protein Size: 297

Molecular Weight: 33 kDa

Gene ID: 1264

NCBI Accession: NM_001299, NP_001290

UniProt: P51911