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INTS12 antibody (N-Term)

INTS12 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN503217
  • Target See all INTS12 Antibodies
    INTS12 (Integrator Complex Subunit 12 (INTS12))
    Binding Specificity
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 9
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
    Host
    • 7
    • 2
    Rabbit
    Clonality
    • 9
    Polyclonal
    Conjugate
    • 9
    This INTS12 antibody is un-conjugated
    Application
    • 9
    • 3
    • 2
    Western Blotting (WB)
    Sequence
    DESLARGIDS SYRPSQKDVE PPKISSTKNI SIKQEPKISS SLPSGNNNGK
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 92%
    Characteristics
    This is a rabbit polyclonal antibody against INTS12. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human INTS12
    Top Product
    Discover our top product INTS12 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 462 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    INTS12 (Integrator Complex Subunit 12 (INTS12))
    Alternative Name
    INTS12 (INTS12 Products)
    Synonyms
    INT12 antibody, PHF22 antibody, GB14117 antibody, fi17f05 antibody, wu:fi17f05 antibody, zgc:86602 antibody, NV50096 antibody, 1110020M19Rik antibody, 2810027J24Rik antibody, 4930529N21Rik antibody, A230056J18Rik antibody, AI666778 antibody, Phf22 antibody, integrator complex subunit 12 antibody, integrator complex subunit 12 S homeolog antibody, INTS12 antibody, LOC409806 antibody, ints12 antibody, ints12.S antibody, CpipJ_CPIJ008030 antibody, Ints12 antibody, Tsp_11238 antibody, Tsp_11342 antibody, Tsp_11345 antibody
    Background
    INTS12 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1) and U2 (RNU2).INTS12 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A, MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1, MIM 180680) and U2 (RNU2, MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM].
    Alias Symbols: INT12, PHF22, SBBI22
    Protein Interaction Partner: POLR2C, APP, SUMO2, UBC, INTS10, INTS5, INTS3, INTS6, INTS1,
    Protein Size: 462
    Molecular Weight
    49 kDa
    Gene ID
    57117
    NCBI Accession
    NM_020395, NP_065128
    UniProt
    Q96CB8
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