FLII antibody (Middle Region)

Catalog No. ABIN503540

Product Details anti-FLII Antibody

Target: FLII (Flightless I Homolog (FLII))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Dog, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FLII antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: LAEDILNTMF DTSYSKQVIN EGEEPENFFW VGIGAQKPYD DDAEYMKHTR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against FLII. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FLII

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1269 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FLII

Target: FLII (Flightless I Homolog (FLII))

Alternative Name: FLII (FLII Products)

Synonyms: FLI antibody, FLIL antibody, Fli1 antibody, 3632430F08Rik antibody, Fliih antibody, im:7141769 antibody, DKFZp459O043 antibody, flightless antibody, FLII, actin remodeling protein antibody, flightless I actin binding protein antibody, protein flightless-1 homolog antibody, FLII, actin remodeling protein S homeolog antibody, Protein flightless-1 homolog antibody, FLII antibody, Flii antibody, flii antibody, LOC585336 antibody, LOC100640615 antibody, flii.S antibody, fli-1 antibody

Background: FLII is a protein with a gelsolin-like actin binding domain and an N-terminal leucine-rich repeat-protein protein interaction domain. The protein is similar to a Drosophila protein involved in early embryogenesis and the structural organization of indirect flight muscle. This gene is located within the Smith-Magenis syndrome region on chromosome 17.This gene encodes a protein with a gelsolin-like actin binding domain and an N-terminal leucine-rich repeat-protein protein interaction domain. The protein is similar to a Drosophila protein involved in early embryogenesis and the structural organization of indirect flight muscle. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FLI, FLIL, Fli1, MGC39265
Protein Interaction Partner: UBC, SUMO2, C14orf166, RTCB, IGF2BP3, PDCD6, LRRFIP1, EIF2B3, RPL27, RFC4, RFC2, PRKDC, NMT1, HNRNPM, MRE11A, KRT18, DHX9, DDX1, PAN2, HSP90AA1, FMNL1, BRCA1, EIF1AX, DGCR8, FBXO25, LRRFIP2, MYD88, ESR1, ACTL6A, GRIP1, CARM1, TRAIP, PRMT1, OPTN, DLST, ACT
Protein Size: 1269

Molecular Weight: 145 kDa

Gene ID: 2314

NCBI Accession: NM_002018, NP_002009

UniProt: Q13045