Search, Find and Buy Antibodies, ELISA Kits and Proteins.
Loading Loading
Order hotline:
phone +1 404 474 4654
fax +1 888 205 9894 (TF)
Details for Product No. ABIN503551

Lymphocyte Cytosolic Protein 1 (LCP1) (N-Term) antibody

Request
Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms CP64, L-PLASTIN, LC64P, LPL, PLS2, cb245, fj24b12, wu:fj24b12, cp64, l-plastin, lc64p, lpl, pls2, plastin-2, AW536232, D14Ertd310e, LCP-1, Pls2, pp65
Epitope
»Alternatives N-Term
Reactivity
»Alternatives Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine), Xenopus laevis, Zebrafish (Danio rerio), Human, Chicken
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN503551
Quantity 50 µg
Price
289.00 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 2 to 3 Business Days
Immunogen The immunogen for anti-LCP1 antibody: synthetic peptide directed towards the N terminal of human LCP1
Sequence FIKIFHGLKSTDVAKTFRKAINKKEGICAIGGTSEQSSVG TQHSYSEEEK
Predicted Reactivity Bovine : 100%, Dog : 100%, Guinea pig : 100%, Horse : 100%, Human : 100%, Mouse : 100%, Pig : 100%, Rat : 100%, African clawed frog : 92%, Chicken : 92%, Rabbit : 92%
Characteristics This is a rabbit polyclonal antibody against LCP1. It was validated on Western Blot using a cell lysate as a positive control. We strive to provide antibodies covering each member of a whole protein family of your interest.
Purification Affinity Purified
Alternative Name LCP1
Background Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. The L isoform is expressed only in hemopoietic cell lineages. However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues. Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues.
Molecular Weight 70kDa
Gene ID 3936
NCBI Accession NP_002289, NM_002298
UniProt P13796
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-LCP1 antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Background publications Klemke, Rafael, Wabnitz et al.: "Phosphorylation of ectopically expressed L-plastin enhances invasiveness of human melanoma cells." in: International journal of cancer. Journal international du cancer, Vol. 120, Issue 12, pp. 2590-9, 2007 (PubMed).

Alternatives for antigen "Lymphocyte Cytosolic Protein 1 (LCP1)", type "Antibodies"
Hosts (18), (10)
Reactivities (22), (3), (3), (3), (2), (1), (1), (1), (1)
Applications (27), (11), (10), (7), (4), (2), (2), (1)
Epitopes (2), (2), (1), (1), (1), (1), (1)
Beacon