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OPTC antibody (C-Term)

OPTC Reactivity: Human, Mouse, Rat, Pig, Dog, Guinea Pig, Cow, Horse, Rabbit, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN503636
  • Target See all OPTC Antibodies
    OPTC (Opticin (OPTC))
    Binding Specificity
    • 11
    • 2
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 24
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Pig, Dog, Guinea Pig, Cow, Horse, Rabbit, Zebrafish (Danio rerio)
    Host
    • 24
    • 1
    Rabbit
    Clonality
    • 24
    • 1
    Polyclonal
    Conjugate
    • 11
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This OPTC antibody is un-conjugated
    Application
    • 9
    • 7
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    Western Blotting (WB)
    Sequence
    LSDNLLDSIP GPLPLSLRSV HLQNNLIETM QRDVFCDPEE HKHTRRQLED
    Predicted Reactivity
    Cow: 77%, Dog: 100%, Guinea Pig: 85%, Horse: 92%, Human: 100%, Mouse: 85%, Pig: 100%, Rabbit: 92%, Rat: 100%, Zebrafish: 83%
    Characteristics
    This is a rabbit polyclonal antibody against OPTC. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human OPTC
    Top Product
    Discover our top product OPTC Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 332 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    OPTC (Opticin (OPTC))
    Alternative Name
    OPTC (OPTC Products)
    Synonyms
    OPTC antibody, optc antibody, OPT antibody, SLRP antibody, dspg3 antibody, optcl antibody, wu:fb81a05 antibody, zgc:101047 antibody, opticin antibody, OPTC antibody, optc antibody, Optc antibody
    Background
    Opticin belongs to class III of the small leucine-rich repeat protein (SLRP) family. Members of this family are typically associated with the extracellular matrix. Opticin is present in significant quantities in the vitreous of the eye and also ocalizes to the cornea, iris, ciliary body, optic nerve, choroid, retina, and fetal liver. Opticin may noncovalently bind collagen fibrils and regulate fibril morphology, spacing, and organization. The opticin gene is mapped to a region of chromosome 1 that is associated with the inherited eye diseases age-related macular degeneration (AMD) and posterior column ataxia with retinosa pigmentosa (AXPC1).Opticin belongs to class III of the small leucine-rich repeat protein (SLRP) family. Members of this family are typically associated with the extracellular matrix. Opticin is present in significant quantities in the vitreous of the eye and also localizes to the cornea, iris, ciliary body, optic nerve, choroid, retina, and fetal liver. Opticin may noncovalently bind collagen fibrils and regulate fibril morphology, spacing, and organization. The opticin gene is mapped to a region of chromosome 1 that is associated with the inherited eye diseases age-related macular degeneration (AMD) and posterior column ataxia with retinosa pigmentosa (AXPC1).
    Alias Symbols: OPT
    Protein Interaction Partner: OSGEP, OPTC,
    Protein Size: 332
    Molecular Weight
    35 kDa
    Gene ID
    26254
    NCBI Accession
    NM_014359, NP_055174
    UniProt
    Q9UBM4
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