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Sec8 antibody (N-Term)

EXOC4 Reactivity: Human, Mouse, Rat, Cow, Horse, Pig, Rabbit, Dog, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN503897
  • Target See all Sec8 (EXOC4) Antibodies
    Sec8 (EXOC4) (Exocyst Complex Component 4 (EXOC4))
    Binding Specificity
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 13
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat, Cow, Horse, Pig, Rabbit, Dog, Zebrafish (Danio rerio)
    Host
    • 12
    • 2
    Rabbit
    Clonality
    • 12
    • 2
    Polyclonal
    Conjugate
    • 14
    This Sec8 antibody is un-conjugated
    Application
    • 12
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    MAAEAAGGKY RSTVSKSKDP SGLLISVIRT LSTSDDVEDR ENEKGRLEEA
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
    Characteristics
    This is a rabbit polyclonal antibody against EXOC4. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human EXOC4
    Top Product
    Discover our top product EXOC4 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 473 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Sec8 (EXOC4) (Exocyst Complex Component 4 (EXOC4))
    Alternative Name
    EXOC4 (EXOC4 Products)
    Synonyms
    CG2095 antibody, Dmel\\CG2095 antibody, Sec8 antibody, Sec8p antibody, dsec8 antibody, fun antibody, SEC8L1 antibody, DKFZp459N1430 antibody, SEC8 antibody, C78892 antibody, Sec8l1 antibody, ALR antibody, si:ch211-92l17.2 antibody, si:rp71-18a24.2 antibody, ATSEC8 antibody, SUBUNIT OF EXOCYST COMPLEX 8 antibody, subunit of exocyst complex 8 antibody, Secretory 8 antibody, exocyst complex component 4 antibody, exocyst complex component 4 L homeolog antibody, Exocyst complex component 4 antibody, subunit of exocyst complex 8 antibody, Sec8 antibody, EXOC4 antibody, CpipJ_CPIJ001354 antibody, Exoc4 antibody, exoc4 antibody, exoc4.L antibody, sec-8 antibody, SEC8 antibody
    Background
    The specific function of this protein remains unknown.The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
    Alias Symbols: MGC27170, REC8, SEC8, SEC8L1, Sec8p
    Protein Interaction Partner: SUMO2, UBC, EXOC2, EXOC7, ATG5, ATG12, BECN1, EXOC8, EGFR, EXOC1, EXOC3, nef, IQCB1, EXOC5, UBD, MYO5A, DTNBP1, CEP63, DISC1, Poc1b, GTF2E2, DLGAP4, DLG3, RALA, GRIN2B, DLG4, MYC,
    Protein Size: 473
    Molecular Weight
    54 kDa
    Gene ID
    60412
    NCBI Accession
    NM_001037126, NP_001032203
    UniProt
    Q8TAR2
    Pathways
    Peptide Hormone Metabolism, Synaptic Vesicle Exocytosis
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