MTMR12 antibody (Middle Region)

Catalog No. ABIN503906

Product Details anti-MTMR12 Antibody

Target: MTMR12 (Myotubularin Related Protein 12 (MTMR12))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTMR12 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RNSARLSSLF PFALLQRHSS KPVLPTSGWK ALGDEDDLAK REDEFVDLGD

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against MTMR12. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MTMR12

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 747 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MTMR12

Target: MTMR12 (Myotubularin Related Protein 12 (MTMR12))

Alternative Name: MTMR12 (MTMR12 Products)

Synonyms: PIP3AP antibody, MTMR12 antibody, 3-PAP antibody, 3Pap antibody, 4932703C11 antibody, C730015A02Rik antibody, Pip3ap antibody, mKIAA1682 antibody, im:7160376 antibody, pip3ap antibody, myotubularin related protein 12 antibody, MTMR12 antibody, mtmr12 antibody, Mtmr12 antibody

Background: MTMR12 inactives phosphatase that plays a role as an adapter for the phosphatase myotubularin to regulate myotubularin intracellular location.Phosphatidylinositide 3-kinase-derived membrane-anchored phosphatidylinositides, such as phosphatidylinositol 3-phosphate (PtdIns(3)P), regulate diverse cellular processes. The protein encoded by this gene functions as an adaptor subunit in a complex with an active PtdIns(3)P 3-phosphatase. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined.
Alias Symbols: 3-PAP, PIP3AP
Protein Interaction Partner: YWHAB, UBC, MTM1,
Protein Size: 747

Molecular Weight: 86 kDa

Gene ID: 54545

NCBI Accession: NM_001040446, NP_001035536

UniProt: Q9C0I1