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RANGAP1 antibody (N-Term)

RANGAP1 Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN503988
  • Target See all RANGAP1 Antibodies
    RANGAP1 (Ran GTPase Activating Protein 1 (RANGAP1))
    Binding Specificity
    • 13
    • 8
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 54
    • 26
    • 25
    • 5
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig
    Host
    • 46
    • 5
    • 2
    • 1
    Rabbit
    Clonality
    • 42
    • 12
    Polyclonal
    Conjugate
    • 30
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This RANGAP1 antibody is un-conjugated
    Application
    • 36
    • 25
    • 19
    • 11
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    MASEDIAKLA ETLAKTQVAG GQLSFKGKSL KLNTAEDAKD VIKEIEDFDS
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against RANGAP1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human RANGAP1
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    Discover our top product RANGAP1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 587 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

  • Target
    RANGAP1 (Ran GTPase Activating Protein 1 (RANGAP1))
    Alternative Name
    RANGAP1 (RANGAP1 Products)
    Synonyms
    Fug1 antibody, RANGAP antibody, SD antibody, ATRANGAP1 antibody, RAN GTPASE-ACTIVATING PROTEIN 1 antibody, RAN GTPase activating protein 1 antibody, RanGAP1 antibody, fug1 antibody, rangap1b antibody, rna1p antibody, C79654 antibody, mKIAA1835 antibody, rangap1 antibody, rangap1a antibody, Protein rna1 antibody, CG9999 antibody, CT28175 antibody, Dmel\CG9999 antibody, RGP1_DROME antibody, Ran antibody, RanGAP antibody, RanGap antibody, RanGap1 antibody, Scl antibody, Sd antibody, Sd-RanGAP antibody, Sd-RanGap antibody, dRanGAP antibody, ranGAP antibody, ranGap antibody, rangap antibody, zgc:154097 antibody, Ran GTPase activating protein 1 antibody, RAN GTPase activating protein 1 antibody, ran GTPase activating protein 1 antibody, Ran GTPase activating protein 1 S homeolog antibody, Ran GTPase activating protein 1 L homeolog antibody, Ran GAP Rna1 antibody, Ran GTPase activating protein antibody, RAN GTPase activating protein 1a antibody, RANGAP1 antibody, TERG_02084 antibody, rangap1.S antibody, Rangap1 antibody, rangap1.L antibody, rna1 antibody, RanGAP antibody, rangap1a antibody
    Background
    RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1,000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGA
    Alias Symbols: Fug1, KIAA1835, MGC20266, SD
    Protein Interaction Partner: SENP2, SENP1, SUMO1, UBE2I, SUMO2, SUMO3, RANBP2, UBC, NEDD8, RNF2, rev, TP53RK, EFTUD1, NIF3L1, RPRD1B, OSGEP, PANK4, THG1L, NSUN2, UFM1, IPO11, SH3GLB1, TPRKB, EEF2K, DBNL, KIAA1279, ACTR2, ACTR3, ARPC1B, SAE1, TPD52L2, PPP2R5D, LPP, CALU, BAG1, ARPC2,
    Protein Size: 587
    Molecular Weight
    63 kDa
    Gene ID
    5905
    NCBI Accession
    NM_002883, NP_002874
    UniProt
    P46060
    Pathways
    M Phase, Protein targeting to Nucleus
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