Ran GTPase Activating Protein 1 (RANGAP1) (N-Term) antibody

Details for Product No. ABIN503988
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Antigen
Synonyms RanGAP1, fug1, rangap1b, rna1p, Fug1, RANGAP, SD, C79654, mKIAA1835, rangap1, rangap1a, ATRANGAP1, RAN GTPASE-ACTIVATING PROTEIN 1, RAN GTPase activating protein 1
Epitope
N-Term
(17), (7), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Human
(49), (25), (21), (14), (14), (11), (5)
Host
Rabbit
(39), (8), (5), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(40), (17), (16), (16), (14), (9), (3), (2), (2), (2)
Pubmed 1 reference available
Quantity 50 µg
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Catalog No. ABIN503988
289.00 $
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Immunogen Synthetic peptide directed towards the N terminal of human RANGAP1
Sequence MASEDIAKLA ETLAKTQVAG GQLSFKGKSL KLNTAEDAKD VIKEIEDFDS
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Guinea pig : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Rabbit : 100 %, Rat : 100 %, Chicken : 80 %
Characteristics This is a rabbit polyclonal antibody against RANGAP1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name RANGAP1
Background RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1,000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGA
Molecular Weight 63 kDa
Gene ID 5905
NCBI Accession NM_002883, NP_002874
UniProt P46060
Research Area Nuclear Transport, Cell Cycle
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 587 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Ran GTPase Activating Protein 1 (RANGAP1) (N-Term) antibody WB Suggested Anti-RANGAP1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Human Muscle
Product cited in: Ewing, Chu, Elisma et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, 2007 (PubMed).

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