NOP58 antibody (Middle Region)

Catalog No. ABIN504082

Product Details anti-NOP58 Antibody

Target: NOP58 (NOP58 Ribonucleoprotein (NOP58))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Dog, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NOP58 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LRTLEDRGIR KISGTGKALA KTEKYEHKSE VKTYDPSGDS TLPTCSKKRK

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 86%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against NOP5/NOP58. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NOP5/NOP58

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 529 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-NOP58 antibody (ABIN504082)

Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, (2004) (PubMed).

Target Details for NOP58

Target: NOP58 (NOP58 Ribonucleoprotein (NOP58))

Alternative Name: NOP5 (NOP58 Products)

Synonyms: NOP5 antibody, NOP5/NOP58 antibody, MSSP antibody, Nol5 antibody, SIK antibody, nop5 antibody, Nap65 antibody, nol5 antibody, wu:fa93b01 antibody, zgc:65841 antibody, NOP58 ribonucleoprotein antibody, NOP58 ribonucleoprotein homolog (yeast) antibody, similar to S. cerevisiae NOP58 (YOR310C) component of Box C/D snoRNPs; 2'-O-methylation of rRNA antibody, NOP58 antibody, Nop58 antibody, nop58 antibody

Background: NOP58 is required for 60S ribosomal subunit biogenesis
Alias Symbols: HSPC120, NOP5, NOP5/NOP58
Protein Interaction Partner: UBC, SUMO2, SUMO3, SUMO1, SUZ12, EED, RNF2, BMI1, rev, CDK11A, CDK15, CDK20, TARDBP, FN1, ESR1, CSNK2A1, WHSC1, RPLP0P6, FTSJ3, NIFK, NOC4L, NHP2, GNL3, RSL1D1, NCSTN, BOP1, RRS1, EBNA1BP2, UTP14A, NOP56, NOLC1, PRPF3, SART1, U2AF1, RPS24, RPS15A, RPS14,
Protein Size: 529

Molecular Weight: 59 kDa

Gene ID: 51602

NCBI Accession: NM_015920, NP_057018

UniProt: Q9Y2X3

Pathways: Protein targeting to Nucleus