GPS1 antibody (N-Term)

Catalog No. ABIN504402

Product Details anti-GPS1 Antibody

Target: GPS1 (G Protein Pathway Suppressor 1 (GPS1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Zebrafish (Danio rerio), Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPS1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PLPVQVFNLQ GAVEPMQIDV DPQEDPQNAP DVNYVVENPS LDLEQYAASY

Predicted Reactivity: Cow: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against GPS1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GPS1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 491 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-GPS1 antibody (ABIN504402)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Target Details for GPS1

Target: GPS1 (G Protein Pathway Suppressor 1 (GPS1))

Alternative Name: GPS1 (GPS1 Products)

Synonyms: COPS1 antibody, CSN1 antibody, Cops1 antibody, Csn1 antibody, R75577 antibody, Sgn1 antibody, im:6909260 antibody, im:7145572 antibody, zgc:154082 antibody, csn1 antibody, ARABIDOPSIS THALIANA FUSCA 6 antibody, ATFUS6 antibody, ATSK31 antibody, CONSTITUTIVE PHOTOMORPHOGENIC 11 antibody, COP11 antibody, COP9 SIGNALOSOME SUBUNIT 1 antibody, EMB78 antibody, EMBRYO DEFECTIVE 78 antibody, FUSCA 6 antibody, SHAGGY-LIKE KINASE 31 antibody, SK31 antibody, G protein pathway suppressor 1 antibody, casein alpha s1 antibody, G protein pathway suppressor 1 L homeolog antibody, COP9 signalosome complex subunit 1 antibody, GPS1 antibody, CSN1S1 antibody, LOC693104 antibody, CC1G_07518 antibody, Bm1_55055 antibody, Gps1 antibody, gps1 antibody, gps1.L antibody, FUS6 antibody, csn-1 antibody

Background: This protein is known to suppress G-protein and mitogen-activated signal transduction in mammalian cells. It shares significant similarity with Arabidopsis FUS6, which is a regulator of light-mediated signal transduction in plant cells. This gene is known to suppress G-protein and mitogen-activated signal transduction in mammalian cells. The encoded protein shares significant similarity with Arabidopsis FUS6, which is a regulator of light-mediated signal transduction in plant cells. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: COPS1, CSN1, MGC71287
Protein Interaction Partner: COPS2, COPS3, COPS4, COPS7A, COPS5, COPS6, COPS8, UBC, cul1, PRKAR2A, FBXO6, NFKBIA, FBXW4, SENP8, vpr, IRF5, NOTCH1, COPS7B, DDB2, DCUN1D1, ASB4, NOD1, CUL2, CUL3, CUL4A, CUL4B, CUL5, NEDD8, JUN, ITPK1, GFER, ERCC8, TP53, POLR2A, DDB1, PSMA6, NF2, CARD11
Protein Size: 491

Molecular Weight: 55 kDa

Gene ID: 2873

NCBI Accession: NM_004127, NP_004118

UniProt: Q13098

Pathways: Cell Division Cycle