FK506 Binding Protein 2, 13kDa (FKBP2) (N-Term) antibody

Details for Product No. ABIN504473
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms 13kDa, FKBP-2, mFKBP13, mFKBP2, RGD1560660, zgc:101826, FKBP-13, PPIase
Epitope
N-Term
(7), (2), (2), (2)
Reactivity
Mouse (Murine), Rat (Rattus), Cow (Bovine), Dog (Canine), Xenopus laevis, Zebrafish (Danio rerio), Human
(12), (8), (4)
Host
Rabbit
(11), (1), (1)
Clonality
Polyclonal
Application
Western Blotting (WB)
(13), (6), (5), (5), (3), (1), (1)
Pubmed 1 reference available
Quantity 50 μg
Options
Shipping to United States (Change)
Availability Will be delivered in 2 to 3 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN504473
289.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Synthetic peptide directed towards the N terminal of human FKBP2
Sequence RLSWFRVLTV LSICLSAVAT ATGAEGKRKL QIGVKKRVDH CPIKSRKGDV
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Goat : 100 %, Human : 100 %, Mouse : 100 %, Rat : 100 %, African clawed frog : 80 %, Zebrafish : 70 %
Characteristics This is a rabbit polyclonal antibody against FKBP2. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name FKBP2
Background FKBP2 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified.The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. This gene has two alternatively spliced transcript variants that encode the same isoform. Multiple polyadenylation sites have been described for this gene, but the full length nature of this gene has not been determined.
Molecular Weight 16 kDa
Gene ID 2286
NCBI Accession NM_004470, NP_004461
UniProt P26885
Research Area Signaling
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 142 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-FK506 Binding Protein 2, 13kDa (FKBP2) (N-Term) antibody WB Suggested Anti-FKBP2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: 721_B cell lysate
Background publications Lim, Hao, Shaw et al.: "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration." in: Cell, Vol. 125, Issue 4, pp. 801-14, 2006 (PubMed).

Validation Images
Did you look for something else?
back to top