XRCC2 antibody (Middle Region)

Catalog No. ABIN504496

Product Details anti-XRCC2 Antibody

Target: XRCC2 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 2 (XRCC2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Dog, Guinea Pig, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This XRCC2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: CLLILDSLSA FYWIDRVNGG ESVNLQESTL RKCSQCLEKL VNDYRLVLFA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 100%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against XRCC2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human XRCC2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 280 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for XRCC2

Target: XRCC2 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 2 (XRCC2))

Alternative Name: XRCC2 (XRCC2 Products)

Synonyms: XRCC2 antibody, 4921524O04Rik antibody, 8030409M04Rik antibody, RAD51 antibody, RecA antibody, RGD1564823 antibody, X-ray repair cross complementing 2 antibody, X-ray repair complementing defective repair in Chinese hamster cells 2 antibody, XRCC2 antibody, Xrcc2 antibody

Background: XRCC2 is a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene is involved in the repair of DNA double-strand breaks by homologous recombination and it functionally complements Chinese hamster irs1, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents.This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene is involved in the repair of DNA double-strand breaks by homologous recombination and it functionally complements Chinese hamster irs1, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DKFZp781P0919
Protein Interaction Partner: RAD51D, MEOX2, WFDC1, NKIRAS1, UBC, RAD51B, RAD51C, RAD51, BLM,
Protein Size: 280

Molecular Weight: 31 kDa

Gene ID: 7516

NCBI Accession: NM_005431, NP_005422

UniProt: O43543

Pathways: DNA Damage Repair