ATP6V1E2 antibody (Middle Region)

Catalog No. ABIN504500

Product Details anti-ATP6V1E2 Antibody

Target: ATP6V1E2 (ATPase, H+ Transporting, Lysosomal 31kDa, V1 Subunit E2 (ATP6V1E2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Sheep, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP6V1E2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LMSTMRNQAR LKVLRARNDL ISDLLSEAKL RLSRIVEDPE VYQGLLDKLV

Predicted Reactivity: Cow: 79%, Dog: 79%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Mouse: 79%, Rabbit: 79%, Rat: 86%, Sheep: 79%

Characteristics: This is a rabbit polyclonal antibody against ATP6V1E2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ATP6V1E2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 226 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ATP6V1E2

Target: ATP6V1E2 (ATPase, H+ Transporting, Lysosomal 31kDa, V1 Subunit E2 (ATP6V1E2))

Alternative Name: ATP6V1E2 (ATP6V1E2 Products)

Synonyms: ATP6E1 antibody, ATP6EL2 antibody, ATP6V1EL2 antibody, VMA4 antibody, 4930500C14Rik antibody, Atp6e1 antibody, E1 antibody, ATPase H+ transporting V1 subunit E2 antibody, ATPase, H+ transporting, lysosomal V1 subunit E2 antibody, Atp6v1e2 antibody, ATP6V1E2 antibody

Background: ATP6V1E2 is a subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. This isoform is essential for energy coupling involved in acidification of acrosome.
Alias Symbols: ATP6E1, ATP6EL2, ATP6V1EL2, MGC9341, VMA4
Protein Interaction Partner: C9orf16, ATP6V1G1, UBC,
Protein Size: 226

Molecular Weight: 26 kDa

Gene ID: 90423

NCBI Accession: NM_080653, NP_542384

UniProt: Q96A05

Pathways: Transition Metal Ion Homeostasis, Proton Transport