CDC34 antibody (Middle Region)

Catalog No. ABIN504598

Product Details anti-CDC34 Antibody

Target: CDC34 (Cell Division Cycle 34 (CDC34))

Binding Specificity: Middle Region

Reactivity: Rat, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC34 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: TLAEYCVKTK APAPDEGSDL FYDDYYEDGE VEEEADSCFG DDEDDSGTEE

Predicted Reactivity: Cow: 100%, Dog: 92%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against CDC34. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CDC34

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 236 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CDC34

Target: CDC34 (Cell Division Cycle 34 (CDC34))

Alternative Name: CDC34 (CDC34 Products)

Synonyms: E2-CDC34 antibody, UBC3 antibody, UBCH3 antibody, UBE2R1 antibody, AI327276 antibody, e2-cdc34 antibody, ubc3 antibody, ube2r1 antibody, CDC34 antibody, DNA6 antibody, Ube2r2 antibody, zgc:55452 antibody, fb34h09 antibody, wu:fb34h09 antibody, wu:fe17e09 antibody, zgc:91847 antibody, cell division cycle 34 antibody, cell division cycle 34 L homeolog antibody, SCF E2 ubiquitin-protein ligase catalytic subunit CDC34 antibody, SCF E2 ubiquitin-protein ligase catalytic subunit antibody, cell division cycle 34 homolog (S. cerevisiae) a antibody, cell division cycle 34 homolog (S. cerevisiae) b antibody, CDC34 antibody, Cdc34 antibody, cdc34.L antibody, cdc34 antibody, cdc34a antibody, cdc34b antibody

Background: CDC34 catalyzes the covalent attachment of ubiquitin to other proteins. CDC34 may be involved in degradation of katenin.The protein encoded by this gene is a member of the ubiquitin-conjugating enzyme family. Ubiquitin-conjugating enzyme catalyzes the covalent attachment of ubiquitin to other proteins. This protein is a part of the large multiprotein complex, which is required for ubiquitin-mediated degradation of cell cycle G1 regulators, and for the initiation of DNA replication. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: E2-CDC34, UBC3, UBE2R1, UBCH3
Protein Interaction Partner: FBXW11, UBC, RBX1, SIAH1, SDCBP, PPARG, ZNRF1, FBXW7, BTRC, UBA1, CDC34, HIST1H2BA, UBI4, MARCH1, MARCH2, GNPDA1, USP5, WARS, RAD23A, ANAPC11, ING4, FBXL2, Rag1, FBXO32, ITCH, NEDD4L, WWP2, TRIM28, RNF7, CUL1, CUL3, VHL, TRIM21, SKP2, CDKN1B, CCNE1, ZFAND
Protein Size: 236

Molecular Weight: 27 kDa

Gene ID: 997

NCBI Accession: NM_004359, NP_004350

UniProt: P49427