MAD2L1 antibody (Middle Region)

Catalog No. ABIN504599

Product Details anti-MAD2L1 Antibody

Target: MAD2L1 (MAD2 Mitotic Arrest Deficient-Like 1 (Yeast) (MAD2L1))

Binding Specificity: Middle Region

Reactivity: Mouse, Rat, Cow, Guinea Pig, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAD2L1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MKCQSYCEPP SYRPMHHEDF KEDLKKFRTK SRTWAGEKSK REMYSRLKKL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against MAD2L1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MAD2L1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 205 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MAD2L1

Target: MAD2L1 (MAD2 Mitotic Arrest Deficient-Like 1 (Yeast) (MAD2L1))

Alternative Name: MAD2L1 (MAD2L1 Products)

Synonyms: HSMAD2 antibody, MAD2 antibody, MXD2 antibody, MXI antibody, bHLHc11 antibody, AA673185 antibody, cb408 antibody, zgc:112133 antibody, mad2 antibody, XMad2 antibody, MAD2L1 antibody, mitotic arrest deficient 2 like 1 antibody, MAX interactor 1, dimerization protein antibody, MAD2 mitotic arrest deficient-like 1 antibody, MAD2 mitotic arrest deficient-like 1 (yeast) antibody, mitotic arrest deficient 2 like 1 S homeolog antibody, MAD2L1 antibody, MXI1 antibody, Mad2l1 antibody, mad2l1 antibody, mad2l1.S antibody

Background: MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate.MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HSMAD2, MAD2
Protein Interaction Partner: ANAPC2, KEAP1, MAD2L1BP, SDCBP, CDC27, BUB1B, TSC22D4, TRIP13, MAD1L1, CDC20, BAG5, UBC, RNF2, OXSR1, RABAC1, ZW10, TP73, MAD2L1, ANAPC4, DAXX, APP, BUB3, CUL3, HSF1, CUEDC2, UBD, NSL1, Gm9174, Cdc16, Cdc23, UBE2C, KLHL13, MAD2L2, NDC80, ADAM17, ESR2, MBL
Protein Size: 205

Molecular Weight: 23 kDa

Gene ID: 4085

NCBI Accession: NM_002358, NP_002349

UniProt: Q13257