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DP1 antibody (Transcription Factor Dp-1) (Middle Region)

Details for Product anti-TFDP1 Antibody No. ABIN504614, Supplier: Login to see New
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Antigen
Synonyms tfdp1l, wu:fb94b07, wu:fc52a06, zgc:55487, TFDP1, dp1, dp-1, drtf1, Dp1, Drtf1, DP1, DRTF1, Dp-1, tfdp1, tfdp1a, hm:zeh1183, zeh1183, zgc:73281
Alternatives
Epitope
Middle Region
(6), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Cow (Bovine), Human, Mouse (Murine), Rat (Rattus), Xenopus laevis, Zebrafish (Danio rerio)
(70), (23), (19), (3), (3), (2)
Host
Rabbit
(42), (29)
Clonality
Polyclonal
Application
Western Blotting (WB)
(62), (26), (20), (12), (11), (5), (4), (2), (2), (1), (1), (1)
Pubmed 1 reference available
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Quantity 50 μg
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Immunogen Synthetic peptide directed towards the middle region of human TFDP1
Sequence SASDLTNGAD GMLATSSNGS QYSGSRVETP VSYVGEDDEE DDDFNENDED
Predicted Reactivity Chicken : 100 %, Human : 100 %, Mouse : 100 %, African clawed frog : 90 %, Bovine : 90 %, Zebrafish : 80 %
Characteristics This is a rabbit polyclonal antibody against TFDP1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name TFDP1 (TFDP1 Antibody Abstract)
Background The E2F transcription factor family regulates the expression of various cellular promoters, particularly those involved in the cell cycle. E2F factors bind to DNA as homodimers or heterodimers in association with dimerization partner DP1. TFDP1 may be the first example of a family of related transcription factors and may have a role in progression of some hepatocellular carcinomas by promoting growth of the tumor cells. The E2F transcription factor family (see MIM 189971) regulates the expression of various cellular promoters, particularly those involved in the cell cycle. E2F factors bind to DNA as homodimers or heterodimers in association with dimerization partner DP1. TFDP1 may be the first example of a family of related transcription factors, see TFDP2 (MIM 602160).
Molecular Weight 45 kDa
Gene ID 7027
NCBI Accession NM_007111, NP_009042
UniProt Q14186
Pathways Cell Division Cycle
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 410 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-DP1 antibody (Transcription Factor Dp-1) (Middle Region) (ABIN504614) WB Suggested Anti-TFDP1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Background publications Datta, Sen, Hagen et al.: "ARF directly binds DP1: interaction with DP1 coincides with the G1 arrest function of ARF." in: Molecular and cellular biology, Vol. 25, Issue 18, pp. 8024-36, 2005 (PubMed).

Catalog No. ABIN504614
$289.00
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