Transcription Factor Dp-1 (TFDP1) (Middle Region) antibody

Details for Product No. ABIN504614
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Antigen
Synonyms tfdp1l, wu:fb94b07, wu:fc52a06, zgc:55487, TFDP1, dp1, dp-1, drtf1, Dp1, Drtf1, DP1, DRTF1, Dp-1, tfdp1, tfdp1a, hm:zeh1183, zeh1183, zgc:73281
Epitope
Middle Region
(6), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Cow (Bovine), Xenopus laevis, Zebrafish (Danio rerio), Human
(61), (26), (23), (15), (12), (12), (12), (3), (2)
Host
Rabbit
(37), (25)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(51), (19), (12), (12), (11), (10), (5), (5), (2), (1), (1)
Pubmed 1 reference available
Quantity 50 µg
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Catalog No. ABIN504614
289.00 $
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Immunogen Synthetic peptide directed towards the middle region of human TFDP1
Sequence SASDLTNGAD GMLATSSNGS QYSGSRVETP VSYVGEDDEE DDDFNENDED
Predicted Reactivity Chicken : 100 %, Human : 100 %, Mouse : 100 %, African clawed frog : 90 %, Bovine : 90 %, Zebrafish : 80 %
Characteristics This is a rabbit polyclonal antibody against TFDP1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name TFDP1
Background The E2F transcription factor family regulates the expression of various cellular promoters, particularly those involved in the cell cycle. E2F factors bind to DNA as homodimers or heterodimers in association with dimerization partner DP1. TFDP1 may be the first example of a family of related transcription factors and may have a role in progression of some hepatocellular carcinomas by promoting growth of the tumor cells. The E2F transcription factor family (see MIM 189971) regulates the expression of various cellular promoters, particularly those involved in the cell cycle. E2F factors bind to DNA as homodimers or heterodimers in association with dimerization partner DP1. TFDP1 may be the first example of a family of related transcription factors, see TFDP2 (MIM 602160).
Molecular Weight 45 kDa
Gene ID 7027
NCBI Accession NM_007111, NP_009042
UniProt Q14186
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 410 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Transcription Factor Dp-1 (TFDP1) (Middle Region) antibody WB Suggested Anti-TFDP1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: MCF7 cell lysate
Background publications Datta, Sen, Hagen et al.: "ARF directly binds DP1: interaction with DP1 coincides with the G1 arrest function of ARF." in: Molecular and cellular biology, Vol. 25, Issue 18, pp. 8024-36, 2005 (PubMed).

Validation Images
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