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HOXA10 antibody (Middle Region)

HOXA10 Reactivity: Mouse, Dog, Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN504647
  • Target See all HOXA10 Antibodies
    HOXA10 (Homeobox A10 (HOXA10))
    Binding Specificity
    • 16
    • 14
    • 12
    • 7
    • 7
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 42
    • 35
    • 20
    • 8
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Mouse, Dog, Rabbit
    Host
    • 53
    • 2
    Rabbit
    Clonality
    • 55
    Polyclonal
    Conjugate
    • 19
    • 6
    • 5
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HOXA10 antibody is un-conjugated
    Application
    • 54
    • 29
    • 14
    • 13
    • 13
    • 12
    • 5
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB)
    Sequence
    GDEEAHASSS AAEELSPAPS ESSKASPEKD SLGNSKGENA ANWLTAKSGR
    Cross-Reactivity
    Dog (Canine), Chicken, Human, Mouse (Murine), Rabbit, Rat (Rattus)
    Predicted Reactivity
    Dog: 100%, Mouse: 92%, Rabbit: 100%
    Characteristics
    This is a rabbit polyclonal antibody against HOXA10. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human HOXA10
    Top Product
    Discover our top product HOXA10 Primary Antibody
  • Application Notes
    WB Suggested Anti-HOXA10 Antibody Titration: 0.2-1 µg/mL
    ELISA Titer: 1:312500
    Positive Control: HepG2 cell lysate.
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 393 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Sugimoto, Nakamura, Okinaka, Hirano, Ono, Shigeno, Shinjo, Ohnishi: "HOXA10 expression induced by Abl kinase inhibitors enhanced apoptosis through PI3K pathway in CML cells." in: Leukemia research, Vol. 32, Issue 6, pp. 962-71, (2008) (PubMed).

  • Target
    HOXA10 (Homeobox A10 (HOXA10))
    Alternative Name
    HOXA10 / HOX1H (HOXA10 Products)
    Synonyms
    HOX1 antibody, HOX1.8 antibody, HOX1H antibody, PL antibody, Hox-1.8 antibody, Hoxa-10 antibody, HOXA10 antibody, Xhoxa9 antibody, hoxa10 antibody, hoxa9-A antibody, Hox-A10 antibody, z-140 antibody, Hoxa10 antibody, RGD1564605 antibody, RGD1566402 antibody, homeobox A10 antibody, homeobox A10 L homeolog antibody, homeobox A10b antibody, homeobox A11 antibody, HOXA10 antibody, Hoxa10 antibody, hoxa10.L antibody, hoxa10b antibody, Hoxa11 antibody
    Background
    In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA10 gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor that may regulate gene expression, morphogenesis, and differentiation. More specifically, it may function in fertility, embryo viability, and regulation of hematopoietic lineage commitment. Alternatively spliced transcript variants encoding different isoforms have been described.In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor that may regulate gene expression, morphogenesis, and differentiation. More specifically, it may function in fertility, embryo viability, and regulation of hematopoietic lineage commitment. Alternatively spliced transcript variants encoding different isoforms have been described.
    Alias Symbols: HOX1, HOX1.8, HOX1H, MGC12859, PL
    Protein Interaction Partner: SPI1, COPS5, CREBBP, PBX1, SNAPC1, EMX1, POLR3D, SIRT2, GMNN, EP300, MEIS1, PTPN6, HOXA10, FOXO1,
    Protein Size: 393
    Molecular Weight
    40 kDa
    Gene ID
    3206
    NCBI Accession
    NM_018951, NP_061824
    UniProt
    P31260
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