AFT7 antibody (N-Term)

Catalog No. ABIN504656

Product Details anti-AFT7 Antibody

Target: AFT7 (Activating Transcription Factor 7 (AFT7))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Pig, Dog, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AFT7 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ASSFEHEFKK AADEDEKKAA AGPLDMSLPS TPDIKIKEEE PVEVDSSPPD

Cross-Reactivity: Dog (Canine), Human, Mouse (Murine), Rat (Rattus)

Predicted Reactivity: Cow: 100%, Dog: 92%, Guinea Pig: 92%, Horse: 84%, Human: 100%, Mouse: 78%, Pig: 100%, Rabbit: 100%, Rat: 84%

Characteristics: This is a rabbit polyclonal antibody against ATF7. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ATF7

Application Details

Application Notes: WB Suggested Anti-ATF7 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:1562500
Positive Control: Human heart.
Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 483 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for AFT7

Target: AFT7 (Activating Transcription Factor 7 (AFT7))

Alternative Name: ATF7 (AFT7 Products)

Synonyms: ATFA antibody, 1110012F10Rik antibody, 9430065F09Rik antibody, AI549878 antibody, C130020M04Rik antibody, ATF7 antibody, fa97a09 antibody, fc25b12 antibody, wu:fa97a09 antibody, wu:fc25b12 antibody, atfa antibody, activating transcription factor 7 antibody, activating transcription factor 7b antibody, ATF7 antibody, Atf7 antibody, atf7b antibody, atf7 antibody

Background: The human ATF7(ATFa) proteins belong to the ATF/CREB family of transcription factors.They mediate the transcriptional activation by the largest E1a protein and can heterodimerize with members of the Jun/Fos family. ATFa proteins have also been found tightly associated with JNK2, a stress-activated kinase. Four variants of ATFa (ATFa0, ATFa1, ATFa2, and ATFa3) have been characterized.
Alias Symbols: ATFA, MGC57182
Protein Interaction Partner: FCER2, TMEM239, FAM9B, CCDC155, MITD1, OCIAD1, TAOK3, URI1, MAPK8, UBC, CREB1, Cebpb, SUMO2, YY1, BCL6, TAF12, TAF4, MAPK9, PTP4A1, PTP4A2, FOS, ATF2, JDP2,
Protein Size: 483

Molecular Weight: 52 kDa

Gene ID: 11016

NCBI Accession: NM_006856, NP_006847

UniProt: B2RMP1