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Myocyte Enhancer Factor 2C (MEF2C) (Middle Region) antibody

Details for Product No. ABIN504660
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Antigen
Synonyms MEF2C, XMEF2C, si:ch211-202e12.2, C5DELq14.3, DEL5q14.3, 5430401D19Rik, 9930028G15Rik, AV011172, Mef2, RGD1563119, id:ibd5026, mef2c, wu:fc05b06, zgc:64184, zgc:85726
Epitope
Middle Region
(29), (22), (17), (17), (15), (14), (14), (10), (10), (8), (6), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Dog (Canine), Human, Rat (Rattus), Mouse (Murine), Pig (Porcine), Zebrafish, Chicken
(230), (112), (80), (73), (61), (49), (48), (1), (1)
Host
Rabbit
(204), (25), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(13), (13), (13), (7), (7), (7), (6), (6), (6), (6), (6), (6), (6), (6)
Application
Western Blotting (WB)
(136), (97), (60), (60), (41), (37), (12), (10), (3), (2), (1)
Pubmed 1 reference available
Quantity 50 µg
Options
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Catalog No. ABIN504660
289.00 $
Plus shipping costs $45.00

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  • +1 404 474 4654
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Immunogen Synthetic peptide directed towards the middle region of human MEF2C
Sequence PPSALSQLGACTSTHLSQSSNLSLPSTQSLNIKSEPVSPP RDRTTTPSRY
Cross-Reactivity Dog (Canine), Chicken, Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
Predicted Reactivity Dog : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Rabbit : 100 %, Rat : 100 %, Zebrafish : 100 %
Purification Affinity Purified
Alternative Name MEF2C
Background MEF2C is a transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. MEF2C controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. MEF2C may also be involved in neurogenesis and in the development of cortical architecture. Isoform 3 and isoform 4, which lack the repressor domain, are more active than isoform 1 and isoform 2.
Molecular Weight 51 kDa
NCBI Accession NM_002397, NP_002388
UniProt Q06413
Research Area Cardiovascular, Hypertrophy, Cardiogenesis, Transcription Factors
Application Notes WB Suggested Anti-MEF2C Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:1562500
Positive Control: COLO205 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 473 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C
Storage Comment Any unfrozen and/or unused material can be stored at 4 °C for short term use (< 1 week), and should not be re-frozen. For longer periods of storage, store at -24 °C
Supplier Images
anti-Myocyte Enhancer Factor 2C (MEF2C) (Middle Region) antibody WB Suggested Anti-MEF2C Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: COLO205 cell lysate
Background publications Nagel, Meyer, Quentmeier et al.: "MEF2C is activated by multiple mechanisms in a subset of T-acute lymphoblastic leukemia cell lines." in: Leukemia, Vol. 22, Issue 3, pp. 600-7, 2008 (PubMed).

Validation Images
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