Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

Retinoic Acid Receptor alpha antibody (Middle Region)

RARA Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN504661
  • Target See all Retinoic Acid Receptor alpha (RARA) Antibodies
    Retinoic Acid Receptor alpha (RARA) (Retinoic Acid Receptor, alpha (RARA))
    Binding Specificity
    • 15
    • 11
    • 11
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 89
    • 39
    • 38
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog, Rabbit
    Host
    • 75
    • 17
    • 1
    Rabbit
    Clonality
    • 68
    • 25
    Polyclonal
    Conjugate
    • 53
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Retinoic Acid Receptor alpha antibody is un-conjugated
    Application
    • 61
    • 41
    • 38
    • 21
    • 15
    • 13
    • 13
    • 11
    • 11
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    EMLENSEGLD TLSGQPGGGG RDGGGLAPPP GSCSPSLSPS SNRSSPATHS
    Cross-Reactivity
    Dog (Canine), Chicken, Human, Mouse (Murine), Rat (Rattus)
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Human: 100%, Mouse: 85%, Rabbit: 100%, Rat: 85%
    Characteristics
    This is a rabbit polyclonal antibody against RARA. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human RARA
    Top Product
    Discover our top product RARA Primary Antibody
  • Application Notes
    WB Suggested Anti-RARA Antibody Titration: 0.2-1 µg/mL
    ELISA Titer: 1:312500
    Positive Control: OVCAR-3 cell lysate.
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 462 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Retinoic Acid Receptor alpha (RARA) (Retinoic Acid Receptor, alpha (RARA))
    Alternative Name
    RAR-alpha / RARA (RARA Products)
    Synonyms
    NR1B1 antibody, RAR antibody, Nr1b1 antibody, RARalpha1 antibody, rar-alpha antibody, etID309833.12 antibody, rara antibody, rara2a antibody, zRAR antibody, zRAR-alpha antibody, zgc:109797 antibody, nr1b1 antibody, RAR-ALPHA1 antibody, HS-RARa antibody, fj66e06 antibody, rara2b antibody, wu:fj66e06 antibody, retinoic acid receptor alpha antibody, retinoic acid receptor, alpha antibody, retinoic acid receptor, alpha a antibody, retinoic acid receptor alpha L homeolog antibody, retinoic acid receptor, alpha b antibody, RARA antibody, Rara antibody, LOC100136372 antibody, raraa antibody, rara.L antibody, rara antibody, rarab antibody
    Background
    Retinoid signaling is transduced by 2 families of nuclear receptors, retinoic acid receptor (RAR) and retinoid X receptor, which form RXR/RAR heterodimers. In the absence of ligand, DNA-bound RXR/RARA represses transcription by recruiting the corepressors NCOR1, SMRT, and histone deacetylase. When ligand binds to the complex, it induces a conformational change allowing the recruitment of coactivators, histone acetyltransferases, and the basic transcription machinery.
    Alias Symbols: NR1B1, RAR
    Protein Interaction Partner: NCOR2, NCOR1, RXRG, MED1, HDAC1, NRIP1, TEKT4, NSD1, NCOA1, CEBPA, ITGB1BP2, SUMO1, UBC, MBD3, CBX5, MTA2, E2F1, WWOX, Sumo2, RXRB, RXRA, AKT1, MMS19, Dlg4, TMEM54, FN1, USP7, NCOA2, SUZ12, EZH2, PML, PSMC5, FAS, PRAM1, TBL1XR1, PRAME, ARID5A, UBE3A, UBQL
    Protein Size: 462
    Molecular Weight
    51 kDa
    Gene ID
    5914
    NCBI Accession
    NM_000964, NP_000955
    UniProt
    P10276
    Pathways
    Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, S100 Proteins
You are here:
Support